Nematophagous, or helminthophagous fungi of the genera , , , , , and , have been used over the years in in vitro and in vivo experiments to control helminth parasites that are potentially zoonotic. These fungi have shown efficacy against the following helminth genera: , , , , , , , and . The results obtained from these experiments, together with studies on soil contamination, suggest the viability of their use as a sustainable and effective strategy to reduce environmental contamination by these zoonotic parasites. Therefore, the aim of this review was to address the role of helminthophagous fungi in the biological control of potentially zoonotic helminths. To this end, we describe (1) a brief history of helminthophagous fungi; (2) a discussion of some potentially zoonotic intestinal parasites; (3) the importance of helminthophagous fungi in the control of nematodes, cestodes, and trematodes; and (4) the potential of helminthophagous fungi as a practical and sustainable strategy.
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http://dx.doi.org/10.3390/pathogens13090741 | DOI Listing |
Pathogens
August 2024
Laboratory of Experimental Parasitology and Biological Control, Vila Velha University-UVV, Vila Velha 29102-920, ES, Brazil.
Acta Trop
June 2024
Department of Veterinary Medicine, Federal University of Viçosa, Viçosa, MG, Brazil.
Helminths are a major challenge in dog breeding, particularly affecting young animals and posing a significant zoonotic risk. The widespread use of anthelmintics to treat gastrointestinal helminth infections in companion animals is common. However, these chemical products generate residues that can have adverse effects on animal, human and environmental health.
View Article and Find Full Text PDFJ Equine Vet Sci
December 2023
Departamento de Medicina Veterinária Preventiva, Laboratório de Doenças Parasitárias (LADOPAR), Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil. Electronic address:
The indiscriminate use of antiparasitics for the treatment of helminths in horses has caused the ineffectiveness of commonly used chemical active principles, therefore, new alternatives such as the use of helminthophagous fungi have been studied. In this context, this study aimed to evaluate the in vitro efficacy of the commercial formulation Bioverm, composed of the fungus Duddingtonia flagrans strain AC001, in the reduction of gastrointestinal nematode larvae in equine feces. In coproculture, the genus Cyathostomum sp.
View Article and Find Full Text PDFPathogens
August 2023
Programa de Pós-Graduação Integrado em Zootecnia, Centro de Ciências Agrárias, Ambientais e Biológicas, Universidade Federal do Recôncavo da Bahia, Cruz das Almas 44380-000, BA, Brazil.
This study aimed to evaluate the effectiveness of the experimental formulation containing chlamydospores of and fungi, against . Two experiments were carried out. The first experiment evaluated the in vitro efficacy using 1 g of the experimental formulation (V1) added to 100 eggs and the control (V2) (without the fungal formulation).
View Article and Find Full Text PDFAppl Microbiol Biotechnol
June 2023
Department of Veterinary Medicine, Federal University of Viçosa, Viçosa, MG, Brazil.
The control of gastrointestinal parasites in animals has become more challenging every year due to parasite resistance to conventional chemical control, which has been observed worldwide. Ovicidal or opportunistic fungi do not form traps to capture larvae. Their mechanism of action is based on a mechanical/enzymatic process, which enables the penetration of their hyphae into helminth eggs, with subsequent internal colonization of these.
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