AI Article Synopsis

  • Magnetoencephalography (MEG) systems measure brain activity by detecting magnetic fields, but they traditionally rely on liquid helium and require magnetically shielded rooms, which complicates their use.
  • Our advanced MEG system features a superconducting magnetic shield and a zero-boil-off system, eliminating the need for frequent helium refills and reducing spatial constraints.
  • Testing demonstrated that our system provided precise magnetic field distributions with estimation errors under 3.5 mm, confirming its practical effectiveness in neuroimaging.

Article Abstract

Magnetoencephalography (MEG) systems are advanced neuroimaging tools used to measure the magnetic fields produced by neuronal activity in the human brain. However, they require significant amounts of liquid helium to keep the superconducting quantum interference device (SQUID) sensors in a stable superconducting state. Additionally, MEG systems must be installed in a magnetically shielded room to minimize interference from external magnetic fields. We have developed an advanced MEG system that incorporates a superconducting magnetic shield and a zero-boil-off system. This system overcomes the typical limitations of traditional MEG systems, such as the frequent need for liquid helium refills and the spatial constraints imposed by magnetically shielded rooms. To validate the system, we conducted an evaluation using signal source estimation. This involved a phantom with 50 current sources of known location and magnitude under active zero-boil-off conditions. Our evaluations focused on the precision of the magnetic field distribution and the quantification of estimation errors. We achieved a consistent magnetic field distribution that matched the source current, maintaining an estimation error margin within 3.5 mm, regardless of the frequency of the signal source current. These findings affirm the practicality and efficacy of the system.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11435837PMC
http://dx.doi.org/10.3390/s24186044DOI Listing

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