AI Article Synopsis

  • Antimicrobial resistance (AMR) is a major global health issue that requires new approaches to tackle infectious diseases.
  • The study explores the antimicrobial properties of various plant species from the biodiverse Mediterranean, identifying promising candidates and their phytochemical constituents.
  • After analyzing 3037 studies, the research found that specific plant species exhibited effective antimicrobial activity, suggesting that these natural agents could aid in combating AMR and contribute to greener veterinary medicine.

Article Abstract

Antimicrobial resistance (AMR) poses a critical global health threat, necessitating innovative strategies to combat infectious diseases. Plants and their extracts offer alternatives/support to traditional antibiotics, and their diverse phytocomplexes with antimicrobial properties can be exploited. The Mediterranean hosts a high number of biodiverse plant species known for their bioactive compounds. This study focuses on identifying plant species and phytochemical constituents with antimicrobial activity against (). Utilizing a systematic literature review and meta-analysis approach, we screened 3037 entries, yielding 70 studies suitable for MIC (minimum inhibitory concentration) annotation. The results highlighted spp., spp. and as the most effective plants with average MICs of, respectively, 0.144 mg/mL, 0.260 mg/mL, and 0.140 mg/mL. These results might help to fight AMR via the discovery of complementary natural antimicrobial agents to support the development of green veterinary pharmacology. Further exploration of these resources promises valuable insights for future support to antimicrobial strategies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11434269PMC
http://dx.doi.org/10.3390/microorganisms12091784DOI Listing

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