AI Article Synopsis
- - The study focuses on a significant pathogen affecting nursing calves globally, analyzing the gut microbiota of dairy calves within their first month of life on a Brazilian farm.
- - Researchers collected fecal samples from 30 calves and tracked their fecal scores, discovering that all calves experienced diarrhea starting on day 5, with all testing positive for the pathogen at some point.
- - The findings indicate that while microbiota richness typically increases as calves age, this growth is hindered by diarrhea, which also alters the composition of the gut microbiota.
Article Abstract
spp. is one of the most important pathogens infecting nursing calves worldwide. This study aimed to investigate the intestinal microbiota of dairy calves during the first month of life and the impact of diarrhea caused by on a Brazilian farm. Fecal samples from 30 calves were collected during the first month of life, and fecal scores were recorded. Samples from the second, third, and fourth days of life were analyzed by DNA sequencing of the 16S rRNA gene. In addition, samples of sixteen calves positive for spp. were retrospectively chosen according to the development of diarrhea: four and two days before diarrhea, at the onset of diarrhea, after four days of diarrhea, at the end of diarrhea, and after six days of diarrhea resolution. Diarrhea was observed in all calves (100%), starting at day 5 of life, and all calves tested positive for in at least one sample. The microbiota richness increased with age but was retarded by diarrhea. Compositional changes associated with infection included increases in , and , as well as decreases in and Lachnospiraceae. In conclusion, infection has the potential to decrease richness and change the composition of the intestinal microbiota of dairy calves.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11434485 | PMC |
| http://dx.doi.org/10.3390/microorganisms12091744 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effects of orally administered clioquinol on the fecal microbiome of horses.
J Vet Intern Med
December 2024
Veterinary Research Scholars Program (VRSP), University of Missouri College of Veterinary Medicine, Columbia, Missouri 65211, USA.
Background: Whereas restoration of fecal consistency after treatment with clioquinol for chronic diarrhea and free fecal water syndrome has been attributed to its antiprotozoal properties, actions of clioquinol on the colonic bacterial microbiota have not been investigated.
Objectives: Characterize the dynamics of fecal microbial diversity before, during, and after PO administration of clioquinol to healthy horses.
Study Design: Experimental prospective cohort study using a single horse group.
[Metabolic Profile of Gut Microbiota and Levels of Trefoil Factors in Adults with Different Metabolic Phenotypes of Obesity].
Mol Biol (Mosk)
December 2024
Pirogov All-Russia National Research Medical University, Moscow, 117997 Russia.
Obesity is associated with changes in the gut microbiota, as well as with increased permeability of the intestinal wall. In 130 non-obese volunteers, 57 patients with metabolically healthy obesity (MHO), and 76 patients with metabolically unhealthy obesity (MUHO), bacterial DNA was isolated from stool samples, and the 16S rRNA gene was sequenced. The metabolic profile of the microbiota predicted by PICRUSt2 (https://huttenhower.
View Article and Find Full Text PDFFaecal metaproteomics analysis reveals a high cardiovascular risk profile across healthy individuals and heart failure patients.
Gut Microbes
December 2025
Hypertension Research Laboratory, School of Biological Sciences, Faculty of Science, Monash, Clayton, Australia.
The gut microbiota is a crucial link between diet and cardiovascular disease (CVD). Using fecal metaproteomics, a method that concurrently captures human gut and microbiome proteins, we determined the crosstalk between gut microbiome, diet, gut health, and CVD. Traditional CVD risk factors (age, BMI, sex, blood pressure) explained < 10% of the proteome variance.
View Article and Find Full Text PDFScreening and identification of antimicrobial peptides from the gut microbiome of cockroach Blattella germanica.
Microbiome
December 2024
MOE Key Laboratory of Bio-Intelligent Manufacturing, School of Bioengineering, Dalian University of Technology, Dalian, Liaoning, 116024, China.
Article Synopsis
- * Researchers identified and validated an AMP, named AMP1, which has broad-spectrum antibacterial activity and minimal toxicity to human cells, showing potential as a safer alternative to traditional antibiotics.
- * The study emphasizes the effective screening of natural AMPs and highlights AMP1's ability to affect bacterial cell wall synthesis and promote wound healing, suggesting it could be a viable option for clinical use.
Exploring the effects of probiotics on olanzapine-induced metabolic syndrome through the gut microbiota.
Gut Pathog
December 2024
Department of Pharmacology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Background: Maintaining gut microbial homeostasis is crucial for human health, as imbalances in the gut microbiota (GM) can lead to various diseases, including metabolic syndrome (MS), exacerbated by the use of antipsychotic medications such as olanzapine (OLZ). Understanding the role of the GM in OLZ-induced MS could lead to new therapeutic strategies. This study used metagenomic analysis to explore the impact of OLZ on the GM composition and examined how probiotics can mitigate its adverse effects in a rat model.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!