A single-domain nanomagnet, shaped like a thin elliptical disk with , has a double-well potential profile with two degenerate energy minima separated by a barrier of a few kT ( = Boltzmann constant and = absolute temperature). The two minima correspond to the magnetization pointing along the two mutually anti-parallel directions along the major axis of the ellipse. At room temperature, the magnetization fluctuates randomly between the two minima, mimicking telegraph noise. This makes the nanomagnet act as a "binary" stochastic neuron (BSN) with the neuronal state encoded in the magnetization orientation. If the nanomagnet is magnetostrictive, then the barrier can be depressed further by applying (electrically generated) uniaxial stress along the ellipse's major axis, thereby gradually eroding the double-well shape. When the barrier almost vanishes, the magnetization begins to randomly assume any arbitrary orientation (not just along the major axis), making the nanomagnet act as an "analog" stochastic neuron (ASN). The magnetization fluctuation then begins to increasingly resemble white noise. The full width at half maximum (FWHM) of the noise auto-correlation function decreases with increasing stress, as the fluctuation gradually transforms from telegraph noise to white noise. Consistent with this trend, the noise spectral density exhibits a 1/f spectrum (at high frequencies) with β decreasing from 2.00 to 1.88 with increasing stress. Stress can thus not only reconfigure a BSN to an ASN, which has its own applications, but it can also perform "noise engineering", i.e., tune the auto-correlation function and power spectral density, having applications in signal processing.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11434151PMC
http://dx.doi.org/10.3390/mi15091174DOI Listing

Publication Analysis

Top Keywords

major axis
12
magnetization fluctuation
8
telegraph noise
8
stochastic neuron
8
white noise
8
auto-correlation function
8
increasing stress
8
spectral density
8
noise
7
magnetization
6

Similar Publications

An efficient heuristic for geometric analysis of cell deformations.

Comput Biol Med

January 2025

SCOPIA Research Group, University of the Balearic Islands, Dpt. of Mathematics and Computer Science, Crta. Valldemossa, Km 7.5, Palma, E-07122, Spain; Health Research Institute of the Balearic Islands (IdISBa), Palma, E-07122, Spain; Laboratory for Artificial Intelligence Applications at UIB (LAIA@UIB), Palma, E-07122, Spain; Artificial Intelligence Research Institute of the Balearic Islands (IAIB), Palma, E-07122, Spain. Electronic address:

Sickle cell disease causes erythrocytes to become sickle-shaped, affecting their movement in the bloodstream and reducing oxygen delivery. It has a high global prevalence and places a significant burden on healthcare systems, especially in resource-limited regions. Automated classification of sickle cells in blood images is crucial, allowing the specialist to reduce the effort required and avoid errors when quantifying the deformed cells and assessing the severity of a crisis.

View Article and Find Full Text PDF

Dysregulated eIF4E-dependent translation is a central driver of tumorigenesis and therapy resistance. eIF4E binding proteins (4E-BP1/2/3) are major negative regulators of eIF4E-dependent translation that are inactivated in tumors through inhibitory phosphorylation or downregulation. Previous studies have linked PP2A phosphatase(s) to activation of 4E-BP1.

View Article and Find Full Text PDF

Prostate cancer is the second most common type of cancer in male worldwide. Stromal-epithelial interaction is thought to have a major impact on cancer development and progression. Previous studies have shown that interaction via soluble factors lead to a reduction in the expression of xCT and AL122023.

View Article and Find Full Text PDF

Nutrition: A non-negligible factor in the pathogenesis and treatment of Alzheimer's disease.

Alzheimers Dement

January 2025

Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Xicheng District, Beijing, China.

Alzheimer's disease (AD) is a degenerative disease characterized by progressive cognitive dysfunction. The strong link between nutrition and the occurrence and progression of AD pathology has been well documented. Poor nutritional status accelerates AD progress by potentially aggravating amyloid beta (Aβ) and tau deposition, exacerbating oxidative stress response, modulating the microbiota-gut-brain axis, and disrupting blood-brain barrier function.

View Article and Find Full Text PDF

Diabetes nephropathy (DN) is a severe diabetic chronic microvascular complication and the major cause of end-stage renal disease (ESRD). Our study aimed to investigate the effects of isoliquiritigenin (ISL) a natural flavonoid compound on DN and to explore the underlying mechanisms. The db/db mice were received intragastric treatments of ISL (5, 10, or 20 mg/kg), vehicle or positive drug metformin (300 mg/kg) once a day for 12 weeks, and the db/m mice treated with vehicle were used as controls.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!