Surface integrity is a critical factor that affects the fatigue resistance of materials. A surface mechanical rolling treatment (SMRT) process can effectively improve the surface integrity of the material, thus enhancing the fatigue property. In this paper, an analysis of variance (ANOVA) and signal-to-noise ratio (SNR) are performed by orthogonal experimental design with SMRT parameters as variables and surface integrity indicators as optimization objectives, and the support vector machine-active learning (SVM-AL) model is proposed based on machine learning theory. The entire model includes three rounds of AL processes. In each round of the AL process, the SMRT parameters with relative average deviation and high output values from cross-validation are selected for the additional experimental supplement. The results show that the prediction accuracy and generalization ability of the SVM-AL model are significantly improved compared to the support vector machine (SVM) model. A fatigue test was also carried out, and the fatigue property of the SMRT specimens predicted by the SVM-AL model is also higher than that of the other specimens.
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http://dx.doi.org/10.3390/ma17184505 | DOI Listing |
Heliyon
January 2025
Cellular and Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran.
The investigation of changes in the membrane of cancer cells holds great potential for biomedical applications. Malignant cells exhibit overexpression of receptors, which can be used for targeted drug delivery, therapy, and bioimaging. Targeted bioimaging is one the most accurate imaging methods with a non-invasive nature, allowing for localization of the malignant cell without disrupting cellular integrity.
View Article and Find Full Text PDFHeliyon
January 2025
University of Coimbra, CEMMPRE, ARISE, Department of Mechanical Engineering, Rua Luís Reis Santos, 3030-788, Coimbra, Portugal.
Recent advancements in aerospace industry demand intricate aero-engine parts, leading to the increased use of titanium alloys, particularly Ti-17, due to its high strength, thermal stability, and corrosion resistance. However, its low thermal conductivity and tool wear tendency pose significant machining challenges, impacting surface integrity, fatigue life, and overall component performance. This study investigates the Wire Electrical Discharge Cutting (WEDC) process, revealing that the mechanism behind improved surface integrity lies in the controlled thermal input, which minimizes phase transformations and reduces residual stresses.
View Article and Find Full Text PDFBioact Mater
April 2025
Department of Gastrointestinal Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, 325035, China.
Long-term exposure to ultraviolet radiation compromises skin structural integrity and results in disruption of normal physiological functions. Stem cells have gained attention in anti-photoaging, while controlling the tissue mechanical microenvironment of cell delivery sites is crucial for regulating cell fate and achieving optimal therapeutic performances. Here, we introduce a mechanically regulated human recombinant collagen (RHC) microcarrier generated through microfluidics, which is capable of modulating stem cell differentiation to treat photoaged skin.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Conservative Department, Faculty of Dentistry, Kafr Al Sheikh University, Kafr Al Sheikh, Egypt.
Background: Short dentin etching, a relatively recent technique, aims to improve resin-dentin bonding by preserving hydroxyapatite crystals within the collagen spaces. This study explores short dentin etching's potential in mitigating over-etching issues in deep proximal dentin/cementum margins, an aspect not previously investigated. This study evaluates the microtensile bond strength (μTBS) and marginal adaptation of two universal adhesives using different etch-and-rinse strategies (15-second and 3-second etching) and self-etch strategies, both immediate and post-thermal cycling and mechanical loading.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Department of Neurosurgery, Guizhou Provincial People's Hospital, Guiyang 550000, China.
Spontaneous intracerebral hemorrhagic stroke (ICH) is a highly aggressive disease, with a high incidence and mortality rate. Iron deposition following ICH leads to oxidative damage and motor dysfunction, significantly impacting the overall quality of life for those affected. Here, a polyphenolic nanomedicine, catechin-based polyphenol nanoparticles surface-modified by thiol-terminated poly(ethylene glycol) (CNPs@PEG), was developed through the oxidative polymerization and self-assembly of catechin, a natural compound in tea.
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