Background: Existing literature on the impact of lipid accumulation product (LAP) and visceral adiposity index (VAI) on severe headache or migraine is limited. This study aims to elucidate the association between LAP and VAI and the prevalence of migraine.
Methods: Data for this study were sourced from the 1999-2004 National Health and Nutrition Examination Survey (NHANES). A database-self-administered questionnaire was used to assess severe headache or migraine. A weighted logistic regression model was employed to assess the relationship between LAP and VAI with migraine prevalence. Complementary analytical approaches included subgroup analysis, restricted cubic spline (RCS), and threshold effect analysis to validate the findings.
Results: In the end, 4572 people were recruited for the research, including 880 with migraine and 3692 without migraine. Following adjustment for the relevant covariables, weighted logistic regression analysis (OR = 1.409, 95% CI: 1.054, 1.883, P = 0.022; OR = 1.288, 95% CI: 1.010, 1.642, P = 0.042) revealed significantly elevated odds of migraine prevalence in participants within the highest tertile (T3) of LAP and VAI than those in the lowest tertile (T1). The nonlinear association between migraine prevalence and both VAI and LAP was further elucidated through a restricted cubic spline. The threshold analysis pinpointed 2.142 (log-likelihood ratio = 0.016) as the critical inflection point for VAI. Subgroup analysis and interaction testing revealed the significant association was independent in different subgroup factors.
Conclusions: The data indicate a robust association between higher levels of LAP and VAI and an increased prevalence of migraine.
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http://dx.doi.org/10.1186/s12944-024-02303-w | DOI Listing |
Hormones (Athens)
January 2025
Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran.
Purpose: Metabolic syndrome (MetS) is a condition of high prevalence worldwide associated with increased risk of cardiovascular disease. The predictive value of novel indices of combined anthropometric and serum lipid parameters as predictors of MetS is, to our knowledge, unexplored. We aimed to assess the 10-year predictive value of three indices of triglyceride-glucose index (TyG), visceral adiposity index (VAI), and lipid accumulation product (LAP) for incidence of MetS in Southeastern Iran.
View Article and Find Full Text PDFSci Rep
January 2025
The Department of Orthopaedic Surgery, Southeast Hospital of Chongqing, Chongqing, 401336, China.
This study aimed to explore the synergistic effect of lipid accumulation product (LAP) and visceral adiposity index (VAI) on diabetes risk, and to evaluate the potential associations of these novel metabolic markers with diabetes. The current cross-sectional survey utilised data from the 2015-2018 National Health and Nutrition Examination Survey (NHANES). The relationship between LAP and VAI levels and diabetes was examined using multiple logistic regression analysis.
View Article and Find Full Text PDFNeurourol Urodyn
December 2024
Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan, Shangdong, China.
Background: The association between different anthropometric indices, including body mass index (BMI), a body shape index (ABSI), lipid accumulation product (LAP), visceral adiposity index (VAI), waist circumference-triglyceride index (WTI), weight-adjusted waist index (WWI), body roundness index (BRI) and the prevalence of overactive bladder (OAB) is unclear. This investigation aims to explore the association among different anthropometric indices and overactive bladder as well as confounding variables.
Methods: Data were obtained from the USA National Health and Nutrition Examination Survey (NHANES) data set between 2005 and 2018, and 15231 participants were included in the study.
Lipids Health Dis
December 2024
Department of Cardiology, Institute of Geriatric Medicine, Beijing Hospital, National Center of Gerontology, Chinese Academy of Medical Sciences, 1 DaHua Road, Beijing, 100730, China.
Background: Frailty poses a considerable public health challenge because of its association with negative health consequences. Although obesity is recognized as a contributor to frailty, conventional measures fail to adequately account for the effects of visceral adiposity. The study aimed to investigate the associations between the visceral adiposity index (VAI) or lipid accumulation product (LAP) and frailty.
View Article and Find Full Text PDFDiabetol Metab Syndr
December 2024
Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Objective: Our aim was to examine the correlation between CVDs and various anthropometric and biochemical indices in the Iranian population.
Methods: 9704 healthy individuals without CVD aged 35-65 were enrolled in our study. The anthropometric indices including Body Adiposity Index (BAI), Abdominal Volume Index (AVI), Body Roundness Index (BRI), Waist to Hip Ratio (WHR), Weight-adjusted Waist Index (WWI), Conicity Index (C-Index), A Body Shape Index (ABSI), Waist to Height Ratio (WHtR), Body Surface Area (BSA), Body Mass Index (BMI), Lipid Accumulation Product (LAP) and Visceral Adiposity Index (VAI) were calculated.
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