AI Article Synopsis

  • Tick-borne bacteria Rickettsia and Coxiella are linked to emerging diseases in humans and animals, and the Hyalomma ticks are known vectors for these pathogens.
  • A study in Pakistan identified seven species of ticks infesting transhumant camels and conducted molecular assays to detect the presence of Rickettsia and Coxiella.
  • The results showed the detection of Rickettsia aeschlimannii, Candidatus Rickettsia shennongii, and Coxiella burnetii, highlighting the potential health risks posed by these ticks to humans.

Article Abstract

Tick-borne bacteria of the genera Rickettsia and Coxiella cause several emerging veterinary and human infectious diseases. Ticks of the genus Hyalomma are medically important vectors due to their potential role in the transmission of pathogens to vertebrate hosts. There is an inadequate knowledge on tick-borne Rickettsia spp. and Coxiella spp. in ticks infesting transhumant camels in Pakistan. In this study, we conducted a molecular survey for screening of Rickettsia spp. and Coxiella spp. in ticks infesting camels. Seven hard tick species including Hyalomma dromedarii, Hyalomma anatolicum, Hyalomma scupense, Hyalomma isaaci, Hyalomma turanicum, Hyalomma asiaticum, and Rhipicephalus sanguineus s.l were confirmed on camels in three distinct physiographic regions of Khyber Pakhtunkhwa, Pakistan. A subset of morphologically identified ticks were subjected to molecular assays for the genetic characterization of ticks and the detection and genetic characterization of Rickettsia and Coxiella species using standard genetic markers. Ticks screened for pathogens resulted in the detection of Rickettsia aeschlimannii and Candidatus Rickettsia shennongii and Coxiella burnetii. The molecular analysis further reveals the presences of an undetermined Rickettsia aeschlimannii-like species, that is making a distinct phylogenetic clade with R. aeschlimannii. The detection of pathogens in camel ticks poses potential health hazards as these ticks frequently bites humans. Molecular screening of Rickettsia spp. and Coxiella spp. associated with camel ticks is a preliminary step toward the surveillance of evaluating their zoonotic threats in the region.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11436945PMC
http://dx.doi.org/10.1038/s41598-024-73663-7DOI Listing

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