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Management of Obesity Hypoventilation Syndrome in Extreme Obesity: A Case Study.
Am J Case Rep
October 2024
Department of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Article Synopsis
- Obesity hypoventilation syndrome (OHS) leads to respiratory issues in obese patients, with complex challenges in critical care for those with extreme obesity, as seen in this case report.
- A 39-year-old man with a body mass index (BMI) over 80 kg/m² faced severe respiratory distress due to OHS, pneumonia, and heart failure, requiring intensive medical interventions like intubation and mechanical ventilation.
- Successful treatment involved a multidisciplinary approach focusing on tailored clinical practices, including managing fluid balance and nutrition, ultimately allowing the patient to recover and return home after 60 days of rehabilitation.
Managing Esophageal Disasters: What to Expect and What to Do.
Thorac Surg Clin
November 2024
Division of Thoracic and Esophageal Surgery, Thomas Jefferson University, Philadelphia, PA, USA. Electronic address:
Esophageal Disasters: A Redundant Term?
Thorac Surg Clin
November 2024
St. Elizabeth's Medical Center, 11 Nevins Street, Suite 201, Brighton, MA 02135, USA. Electronic address:
Defining the clinical benefits of adding a neurokinin-1 receptor antagonist to control chemotherapy-induced nausea and vomiting in moderately emetogenic chemotherapy: a systematic review and meta-analysis of the clinical practice guidelines for antiemesis 2023 from the Japan society of clinical oncology.
Int J Clin Oncol
November 2024
Department of Pharmacy, Gifu University Hospital, 1-1 Yanagido, Gifu, Gifu, 501-1194, Japan.
Background: Chemotherapy-induced nausea and vomiting (CINV) commonly affects patient quality of life and the overall effectiveness of chemotherapy. This study aimed to evaluate whether adding neurokinin-1 receptor antagonists (NK1RAs) to 5-hydroxytryptamine-3 receptor antagonists (5-HTRAs) and corticosteroids provides clinically meaningful benefits in preventing CINV in patients receiving moderately emetogenic chemotherapy (MEC).
Methods: We conducted a systematic review of PubMed, Cochrane Library, and Ichushi-Web to identify clinical studies evaluating NK1RAs combined with 5-HTRAs and dexamethasone for managing CINV in MEC.
Recanalization of port-superior mesenteric vein thrombosis with long-term anticoagulant therapy after failed early anticoagulant therapy.
Surg Case Rep
June 2024
Department of Emergency and Critical Care Medicine, Nippon Medical School Hospital, 1-1-5, Sendagi, Bunkyo-Ku, Tokyo, 113-8603, Japan.
Background: Anticoagulant therapy with heparin is the first-line treatment for acute mesenteric vein thrombosis and is effective in improving outcomes. Conversely, patients with failed early anticoagulant therapy occasionally develop bowel infarction requiring surgery. The efficacy of long-term anticoagulant therapy on recanalizing mesenteric vein thrombosis in patients with failed early anticoagulant therapy remains unclear.
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