Gut microbiota and eye diseases: A review.

Medicine (Baltimore)

Eye Center, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Published: September 2024

AI Article Synopsis

  • Recent studies indicate that changes in gut microbiota are significantly associated with the progression of various diseases, including those affecting eye health.
  • The review focuses on the connection between gut microbiome and specific eye conditions, such as ocular surface diseases and immune-mediated eye disorders, highlighting the microbiota's influence on immune regulation and metabolites.
  • Potential strategies like probiotics, antibiotics, dietary changes, and fecal transplants are examined as promising approaches to address these issues and provide new therapeutic options for eye care.

Article Abstract

Recent studies reveal that alterations in gut microbiota play a significant role in the progression of various diseases, including those affecting the eyes. The association between gut microbiota and eye health is an emerging focus of research. This review seeks to summarize the connection between the gut microbiome and specific eye conditions, such as ocular surface diseases, funduscopic disorders and immune-mediated eye diseases. Gut microbiota may influence these conditions by regulating the immune system or altering metabolites, thereby contributing to disease development. Strategies like probiotics, antibiotics, dietary modifications, and fecal transplants show promise in addressing these issues. This review examines how the gut microbiome may be linked to the pathogenesis of eye diseases, providing fresh therapeutic perspectives for ophthalmology.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441905PMC
http://dx.doi.org/10.1097/MD.0000000000039866DOI Listing

Publication Analysis

Top Keywords

gut microbiota
16
eye diseases
12
microbiota eye
8
gut microbiome
8
gut
6
eye
5
diseases
5
diseases review
4
review studies
4
studies reveal
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!