Little impact of new mutations on mammalian trait variation.

PLoS Biol

The Jackson Laboratory, Bar Harbor, Maine, United States of America.

Published: September 2024

AI Article Synopsis

  • New mutations are the main source of genetic variation, but their role in influencing traits isn't fully clear.
  • A recent study in PLOS Biology explores this issue, specifically in mice.
  • The findings indicate that new mutations tend to have only a minimal impact on certain traits.

Article Abstract

New mutations provide the source of all genetic variation but their impact on trait variation remains poorly understood. A new study published in PLOS Biology addresses this question, finding that new mutations exert only weak effects on some traits in mice.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11432828PMC
http://dx.doi.org/10.1371/journal.pbio.3002825DOI Listing

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