To enhance engagement and educational outcomes, game-based learning has been introduced into undergraduate and graduate medical education programs. Using a free website, "PM&R Connections", a serious game, was created to provide trainees with an alternative method of reviewing content to identify knowledge gaps to direct studying. The game was used by 19/33 trainees and 92.3% of users required <10 minutes to complete a puzzle. 76.9% of users found the tool helpful, 69.2% recommended the game, and 92.3% desired more puzzles to be developed. Confusion on how to play and intimidation were the most reported barriers to play, and only 46% of users changed their study habits. The positive feedback and desire for more puzzles to be developed provide a foundation to further develop the game.
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http://dx.doi.org/10.1097/PHM.0000000000002620 | DOI Listing |
PLoS Biol
January 2025
State Key Laboratory of Genetic Engineering, School of Life Sciences, Department of Infectious Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
The peritrophic matrix (PM) acts as a physical barrier that influences the vector competence of mosquitoes. We have previously shown that gut microbiota promotes PM formation in Anopheles stephensi, although the underlying mechanisms remain unclear. In this study, we identify that the cell wall components of gut commensal bacteria contribute to PM formation.
View Article and Find Full Text PDFEnviron Monit Assess
January 2025
School of Mathematical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.
This study investigates the effectiveness and efficiency of two topological data analysis (TDA) techniques, the conventional Mapper (CM) and its variant version, the Ball Mapper (BM), in analyzing the behavior of six major air pollutants (NO, PM, PM, O, CO, and SO) across 60 air quality monitoring stations in Malaysia. Topological graphs produced by CM and BM reveal redundant monitoring stations and geographical relationships corresponding to air pollutant behavior, providing better visualization than traditional hierarchical clustering. Additionally, a comparative analysis of topological graph structures was conducted using node degree distribution, topological graph indices, and Dynamic Time Warping (DTW) to evaluate the sensitivity and performance of these TDA techniques.
View Article and Find Full Text PDFN Engl J Med
January 2025
From the Division of Health Services, Outcomes, and Policy, Department of Radiation Oncology, Emory University School of Medicine, and the Department of Health Policy and Management, Emory Rollins School of Public Health - both in Atlanta (P.M.G.S.); the Center for Bioethics and Humanities, SUNY Upstate Medical Center, Syracuse, NY (R.E.F.); and the Department of Internal Medicine, University of Colorado-Anschutz Medical Center, Aurora (L.C.).
Anal Chem
January 2025
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, Jilin, China.
Exosomes are small endosome-derived extracellular vesicles that participate in cell-cell communication, particularly in the context of tumorigenesis, and their secretion is influenced by the tumor microenvironment. While previous studies suggest that mechanical forces may enhance exosome release, the direct relationship between these forces and exosome secretion needs to be further characterized. Here, we utilized dual-color CD63 reporter-based high-speed live-cell imaging to visualize how mechanical forces influence exosome release in situ.
View Article and Find Full Text PDFAfr J Reprod Health
December 2024
Bursa City Hospital Department of Obstetrics and Gynecology, Bursa Turkey.
The discharge time of the postpartum woman is an issue related to emotional readiness and hospital policies and should be evaluated by the nurse. The feeling of readiness of the postpartum woman is the key in making the decision to discharge.The objective of the study is to evaluate the discharge readiness of puerperium and to determine the factors affecting.
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