The discussions of our paper provide insights into the practical considerations of the latent exchangeability prior while also highlighting further extensions. In this rejoinder, we briefly summarize the discussions and provide comments.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1093/biomtc/ujae087 | DOI Listing |
J Environ Manage
January 2025
Economics and Management (Business) School, Shandong Agricultural University, Tai' an, 271018, PR China. Electronic address:
In recent years, the development of Forest Carbon Sink Project (FCSP) has become a key focus within forestry sector. Despite this, decision-makers often lack reliable tools to assess forest owners' willingness to engage in this project. This study aims to develop, validate and evaluate a rational value perception scale as the tool to understand the willingness of forest manager.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Jiao Tong University, Shanghai, 200240, China.
Sulfur-fluoride exchange (SuFEx) reaction is an emerging class of click chemistry reaction. Owing to its efficient reactivity under physiological conditions, SuFEx reaction is used to construct covalent protein drugs. Herein, a covalent affibody-molecular glue drug conjugate nanoagent is reported, which can irreversibly bind with its target protein through proximity-enabled SuFEx reaction.
View Article and Find Full Text PDFSci Rep
January 2025
College of computer science and technology, China University of Petroleum (East China), No.66 Changjiang West Road, Huangdao, Qingdao, 266580, Shandong, China.
Addressing the issues of inadequate information exchange among subsequences in the operational time series of water injection pumps, leading to low accuracy and high false alarm rates in anomaly detection, this paper proposes a multidimensional time series anomaly detection method for water injection pump operations, leveraging Long Short-Term Memory Autoencoder augmented with Attention Mechanism (LSTMA-AE) and mechanistic constraints. The LSTMA-AE framework encompasses three primary modules: a Time Feature Extraction Module (Encoder), an Attention Layer, and a Data Reconstruction Module (Decoder). The Encoder captures temporal dependencies and features within the input sequences, mapping the input data into a higher-dimensional space.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Laboratoire de Géologie, Ecole Normale Supérieure, CNRS, Institut Pierre-Simon Laplace, Université Paris Sciences et Lettres, Paris 75005, France.
The insulative properties of soil organic carbon (SOC) and surface organic layers (moss, lichens, litter) regulate surface-atmosphere energy exchanges in the Arctic through a coupling with soil temperatures. However, a physical description of this process is lacking in many climate models, potentially biasing their high-latitude climate predictions. Using a coupled surface-atmosphere model, we identified a strong feedback loop between soil insulation, surface air temperature, and snowfall.
View Article and Find Full Text PDFBlood Adv
January 2025
KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.
Allosteric regulation of ADAMTS13 (A Disintegrin And Metalloproteinase with ThromboSpondin type-1 motif, member 13) activity involves an interaction between its Spacer (S) and CUB1-2 domains to keep the enzyme in a closed, latent conformation. Monoclonal antibodies (mAb) uncouple the S-CUB interaction to open the ADAMTS13 conformation and thereby disrupt the global enzyme latency. The molecular mechanism behind this mAb-induced allostery remains poorly understood.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!