A heterogeneous continuous age-structured model of mumps with vaccine.

Infect Dis Model

Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), School of Mathematics and Statistics, Southwest University, Chongqing, 400715, China.

Published: March 2025

In classical mumps models, individuals are generally assumed to be uniformly mixed (homogeneous), ignoring population heterogeneity (preference, activity, etc.). Age is the key to catching mixed patterns in developing mathematical models for mumps. A continuous heterogeneous age-structured model for mumps with vaccines has been developed in this paper. The stability of age-structured models is a difficult question. An explicit formula of was defined for the various mixing modes (isolation, proportional and heterogeneous mixing) with or without the vaccine. The results show that the endemic steady state is unique and locally stable if  > 1 without any additional conditions. A number of numerical examples are given to support the theory.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11424798PMC
http://dx.doi.org/10.1016/j.idm.2024.09.004DOI Listing

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