Acidic oral environments may trigger systemic contact dermatitis via ionization of metals, including palladium. A patch test revealed a late delayed positive response to palladium, emphasizing the need for nuanced diagnostic approaches for allergy management.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11426033PMC
http://dx.doi.org/10.1016/j.jacig.2024.100333DOI Listing

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