Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/rmv.2587 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Maternal Incarceration and Health Risk Behaviors Among Adolescents: A Latent Class Analysis.
Int J Offender Ther Comp Criminol
January 2025
Diana R. Garland School of Social Work, Baylor University, Houston, TX, USA.
Most studies on the impact of maternal incarceration on adolescent health risk behaviors have focused on singular, separated behaviors, even though these behaviors often cluster and co-occur. This study used the FFCWS dataset to examine the association between maternal incarceration and the aggregation of health risk behaviors among adolescents. Latent class analysis suggested the four-class model had the optimal model fit.
View Article and Find Full Text PDFLocal Adaptive Fusion Regression (LAFR) for Local Linear Multivariate Calibration: Application to Large Datasets.
Appl Spectrosc
January 2025
Department of Chemistry, Idaho State University, Pocatello, Idaho, USA.
Impeding linear calibration models from accurately predicting target sample analyte amounts are the target sample-wise deviations in measurement profiles (e.g., spectra) relative to calibration samples.
View Article and Find Full Text PDFNavigating antiphospholipid syndrome: from personalized therapies to cutting-edge research.
Rheumatol Adv Pract
January 2025
Department of Internal Medicine, Hospital General "Dr. Manuel Gea González", Ciudad de Mexico, Mexico.
APS is an autoimmune disorder characterized by thrombosis and pregnancy complications, primarily driven by aPLs such as LA, aCL and anti-β2 glycoprotein I (a-β2GPI). Despite advances in anticoagulation therapies, managing refractory APS cases remains challenging. Emerging therapies, including rituximab, eculizumab and HCQ, show potential in addressing the underlying mechanisms of APS.
View Article and Find Full Text PDFMycophenolate mofetil: an update on its mechanism of action and effect on lymphoid tissue.
Front Immunol
January 2025
Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Introduction: Mycophenolate mofetil (MMF) is an immunosuppressive drug administered in the management of both autoimmune diseases and organ transplantation. The main aims of the study were: (a) to obtain information regarding the safety of using MMF in respect of its effect on normal T and B cells in lymphoid tissues; (b) to investigate whether the generation of inducible Foxp3-expressing regulatory T cells (Treg) might constitute additional mechanisms underlying the immunosuppressive properties of MMF.
Methods: The effect of MMF ( studies) and its active metabolite, mycophenolic acid, ( studies) on murine CD4 and CD8 T cells as well as B cells was determined, regarding: (a) absolute count, proliferation and apoptosis of these cells ( studies); (b) absolute count of these cells in the head and neck lymph nodes, mesenteric lymph nodes and the spleen ( studies).
Molecular profiling of frontal and occipital subcortical white matter hyperintensities in Alzheimer's disease.
Front Neurol
January 2025
Department of Neurology, Massachusetts General Hospital, Charlestown, MA, United States.
White matter hyperintensities (WMHs) are commonly detected on T2-weighted magnetic resonance imaging (MRI) scans, occurring in both typical aging and Alzheimer's disease (AD). Despite their frequent appearance and their association with cognitive decline in AD, the molecular factors contributing to WMHs remain unclear. In this study, we investigated the transcriptomic profiles of two commonly affected brain regions with coincident AD pathology-frontal subcortical white matter (frontal-WM) and occipital subcortical white matter (occipital-WM)-and compared with age-matched cognitively intact controls.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!