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Chronic heart failure (CHF) is one of the most common diseases with a prevalence of 1-2% in adults, disproportionately affecting the elderly. Despite consistent drug therapy, physical activity (PA) is an integral part of current guidelines. Yet adherence to regular PA and exercise interventions is poor and potential predictors and barriers to PA remain elusive. We examined the effects of a telemonitoring-based exercise intervention in 699 CHF patients in a prospective, randomized-controlled (1:1), multicenter trial. The study was registered in the German Clinical Trials Register under DRKS00019022 on 28.05.2020. For both, the exercise and control group, self-reported PA (MET*h/week) increased and sedentary behavior declined during the 12-month intervention period. In the exercise group, daily step count as analyzed via activity trackers remained stable (pre: 6459 [4016] steps/day, post: 6532 [3858] steps/day; p = 0.621). The average number of completed exercise instruction videos provided via an online application was 1.50 [1.44] videos/week at the beginning and gradually decreased to 1.00 [1.50] videos/week; p < 0.001). Multivariate regression model revealed that exercise-related PA (MET*h/week) and exercise capacity (W) at baseline, CHF severity, atrial fibrillation and age predicted changes in self-reported exercise-related PA (R = 0.396). Furthermore, the BMI and the average number of completed videos per week at baseline were associated with the change in completed videos over the course of the study (R = 0.251). Our results show the influence of certain baseline characteristics as barriers and predictors of PA progression. Therefore, exercise programs should pay attention to patients' individual conditions to set achievable goals, and eventually affect the adherence and sustainability of exercise-focused interventions.
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http://dx.doi.org/10.1038/s41598-024-70371-0 | DOI Listing |
J Am Chem Soc
December 2024
College of Materials, Institute of Artificial Intelligence, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, iChEM, Fujian Key Laboratory of Advanced Materials, College of Energy, Xiamen University, Xiamen 361005, China.
Nickel-iron-based catalysts are recognized for their high efficiency in the oxygen evolution reaction (OER) under alkaline conditions, yet the underlying mechanisms that drive their superior performance remain unclear. Herein, we revealed the molecular OER mechanism and the structure-intermediate-performance relationship of OER on a phosphorus-doped nickel-iron nanocatalyst (NiFeP). NiFeP exhibited exceptional activity and stability with an overpotential of only 210 mV at 10 mA cm in 1 M KOH and a cell voltage of 1.
View Article and Find Full Text PDFExp Physiol
December 2024
School of Health Sciences, Massey University, Wellington, New Zealand.
Dynamic resistance exercise (RE) produces sinusoidal fluctuations in blood pressure, with hypotension and cerebral hypoperfusion commonly observed immediately following RE. Whether the cerebral vasculature adapts to these regular blood pressure challenges is unclear. This study examined the cerebrovascular response to post-dynamic RE orthostasis.
View Article and Find Full Text PDFExp Physiol
December 2024
Exercise Biological Center, China Institute of Sport Science, Beijing, China.
The impact of housing temperature on exercise-induced metabolic adaptations is not well understood, despite extensive research on the benefits of exercise for metabolic health. The aim of this study was to elucidate how housing temperatures influence the molecular responses and metabolic benefits of exercise in mice. Male C57BL/6N mice were housed at either room temperature (RT, 21°C) or in a thermoneutral environment (TN, 29°C) and subjected to either a 6-week or acute exercise regimen.
View Article and Find Full Text PDFNano Lett
December 2024
Alan G. MacDiarmid Institute, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, P. R. China.
Developing highly efficient non-iridium-based active sites for acidic water splitting is still a huge challenge. Herein, unique Ru-B-Cr moieties have been constructed in RuO nanofibers (NFs) to activate Ru sites for water electrolysis, which overcomes the bottleneck of RuO-based catalysts usually possessing low activity for the hydrogen evolution reaction (HER) and poor stability for the oxygen evolution reaction (OER). The fabricated Cr, B-doped RuO NFs exhibit low overpotentials of 205 and 379 mV for acidic HER and OER at 1 A cm with outstanding stability lasting 1000 and 188 h, respectively.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
Department of Chemical and Biological Engineering, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Cobalt is recognized as an active catalyst in ethane dehydroaromatization (EDA) reactions due to its efficient ethane cracking capability. In order to optimize cobalt's strong ethane cracking capability, it was loaded onto HZSM-5 zeolite through impregnation. This study was conducted with Co-loaded HZSM-5 catalysts with an incipient wetness impregnation method and witnessed an increase of catalytic activity with a long induction period.
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