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The CREscendoing promise of HDAC targeting to limit atherosclerosis.
Immunity
March 2025
Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria. Electronic address:
The factors that modulate the inflammatory response in atherosclerosis are not well defined. In this issue of Immunity, Asare et al. examine the impact of a cis-regulatory element (CRE) that controls expression of HDAC9 and find that HDAC9-mediated deacetylation of NLRP3 might be the mechanism by which genetic variants in this conserved CRE influence the inflammation associated with human atherosclerosis.
View Article and Find Full Text PDFSecuring Global Health in the Face of Changing U.S. Policy: The Case for Strengthening National Public Health Institutes.
Int J Health Plann Manage
March 2025
IANPHI, Saint-Maurice, France.
Following the announcement by the new American administration of a pause and review of funding to international aid programmes, we comment on the potential effect on global health security and argue for increased recognition of the role of National Public Health Institutes (NPHIs) to mitigate the impacts.
View Article and Find Full Text PDFWhen Help Is Harm: Health, Lookism and Self-Improvement in the Manosphere.
Sociol Health Illn
March 2025
Faculty of Computer Science, Dalhousie University, Halifax, Canada.
How do online communities impact men's health? How does hegemonic masculinity harm men's health? In this paper, we analyse an online looksmaxxing community that receives 6 million unique visitors per month and is aimed at men seeking to improve their appearance. We qualitatively analysed 8072 discussion board comments in total. Our findings first demonstrate how users apply a hegemonic masculine gaze as they critique men's bodies (e.
View Article and Find Full Text PDF'I'm glad my baby has weaned so I don't need to make that decision.' Understanding breastfeeding-related COVID-19 vaccine narratives on social media.
Health Promot J Austr
April 2025
School of Population Health, Curtin University, Perth, Western Australia, Australia.
Issue Addressed: During the coronavirus disease 2019 (COVID-19) pandemic, the infodemic has been highly visible. Vaccine-related advice and evidence-based guidelines for breastfeeding women have lagged, and, at times have been contradictory and confusing. Breastfeeding is an important public health issue with long-lasting health benefits for infants and mothers.
View Article and Find Full Text PDFImpact of Aromatase and ESR1 expression in SAT on insulin resistance and T2D in obese men.
J Clin Endocrinol Metab
March 2025
Biochemistry Section, Faculty of Chemical Sciences and Technologies, University of Castilla-La Mancha, Avda. Camilo José Cela 10, 13071 Ciudad Real, Spain.
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