A G3P[3] bat rotavirus can infect cultured human cholangiocytes and cause biliary atresia symptom in suckling mice.

Virol Sin

Research Unit of Key Technologies for Prevention and Control of Virus Zoonoses, Chinese Academy of Medical Sciences, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, 130122, China. Electronic address:

Published: December 2024

• Bat rotavirus strain MSLH14 (G3P[3]) can infect human cholangiocytes . • MSLH14 can cause suckling mice biliary atresia symptom, indicating potential public health risks. • MSLH14 have the potential for establishing a biliary atresia animal model.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11738784PMC
http://dx.doi.org/10.1016/j.virs.2024.09.009DOI Listing

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