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In this study, the effect of Torreya grandis protein enzymatic hydrolysates (TGPH)/alginate dialdehyde (ADA) complexes in the internal aqueous phase on the physical stability of the water-in-oil-in-water (W/O/W) emulsions was studied. In the case of TGPH/ADA emulsions, the presence of ADA decreased the apparent viscosity of the emulsions and changed the flow behavior from shear thinning to Newtonian, leading to a decrease in volume-weighted average droplet diameter (D) of the emulsions. Additionally, the emulsions at the TGPH/ADA ratios of 1:1 showed a lower turbiscan stability index (TSI) value, and smaller change in delta backscattering signal, compared to the emulsions. The enhanced pH stability and storage stability of the emulsions at the TGPH/ADA ratios of 1:1 was due to the formation of Schiff bases between TGPH and ADA. These results suggested that the covalent cross-linking of TGPH with ADA could significantly improve the stability of the emulsions, which provided an effective means for the development of new food-grade protein-polysaccharide complexes stabilized emulsions.
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http://dx.doi.org/10.1016/j.ijbiomac.2024.136002 | DOI Listing |
Appl Microbiol Biotechnol
December 2024
Laboratory of Environmental Bioprocesses, Centre of Biotechnology of Sfax, University of Sfax, Sfax, Tunisia.
In the present investigation, 13% ± 0.84 of the extracted and purified phycocyanin from Phormidium versicolor was obtained, with a purity of 0.69 following dialysis.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
December 2024
Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India.
Idiopathic pulmonary fibrosis (IPF) is a severe and progressive lung disorder with an average survival rate of 3 to 5 years. IPF presents a significant challenge in clinical management, necessitating novel therapeutic approaches. Nanostructured lipid carriers (NLCs) have proven to be promising vehicles for targeted drug delivery to the lung tissues.
View Article and Find Full Text PDFFood Chem
December 2024
Engineering Research Center of Health Food Design & Nutrition Regulation, Dongguan Key Laboratory of Typical Food Precision Design, China National Light Industry Key Laboratory of Healthy Food Development and Nutrition Regulation, School of Life and Health Technology, Dongguan University of Technology, Dongguan 523808, China.
This study examined the effect of quinone concentration on covalent interaction between β-lactoglobulin (β-Lg) and 4-methylbenzoquinone (4MBQ). β-Lg-4MBQ-0.2, β-Lg-4MBQ-0.
View Article and Find Full Text PDFTher Deliv
December 2024
Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, India.
Aim: Voriconazole (VRZ) is highly effective in treating invasive pulmonary aspergillosis (IPA), in addition to hepatotoxicity. Therefore, the current study focuses on the development and characterization of voriconazole-loaded microspheres (VRZ@PCL MSPs) to augment pulmonary localization and antifungal efficacy.
Methods: VRZ@PCL MSPs were fabricated by using the o/w emulsion method.
Int J Biol Macromol
December 2024
SKL of Marine Food Processing & Safety Control, Dalian Polytechnic University, Dalian 116034, PR China; National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China; Engineering Research Center of Special Dietary Food, the Education Department of Liaoning Province, Dalian 116034, PR China. Electronic address:
This research endeavored to engineer robust delivery matrices for bioactives, specifically benzyl isothiocyanate (BITC), by harnessing the synergistic covalent and non-covalent interactions between fish skin gelatin (FSG) and proanthocyanidins (PC) to synthesize novel composite emulsions. The objective was to delineate the influence of these molecular interactions on the emulsion's structural integrity and stability, which are pivotal for the efficacious encapsulation and controlled release of BITC. Employing a suite of analytical techniques, including Fourier transform infrared spectroscopy (FTIR), fluorescence spectroscopy, and contact angle measurements, the study delineated the predominant molecular forces at play within the FSG-PC complex, identifying electrostatic and hydrophobic interactions as the cornerstones of this interaction.
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