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Identifying meaningful aspects of health and concepts of interest for assessment in systemic lupus erythematosus: implications for digital clinical measure development.
J Patient Rep Outcomes
December 2024
Department of Rheumatology, Hôpitaux Universitaires de Strasbourg, INSERM UMR-S 1109, Centre National de Référence des Maladies Auto-immunes Systémiques Rares (RESO), Strasbourg, France.
Objectives: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with heterogeneous clinical manifestations which significantly impacts the daily lives of patients. Herein, we aimed to (i) investigate patients' perspectives on and experience with SLE; (ii) identify meaningful aspects of health (MAHs) and concepts of interest (COIs) in SLE that could be evaluated using digital clinical measures (DCMs); and (iii) identify target DCMs for their assessment.
Methods: A mixed-methods, multistep approach was deployed for (i) exploring patients' experience with SLE through a social media listening study and focused group discussions with patients; (ii) mapping patients' experiences to define MAHs and identify COIs measurable using DCMs; (iii) selecting DCMs for the target COIs; and (iv) identifying types of wearable sensors for measuring COIs in the patients.
Rectification of Erroneous Chronological Dating of Three Anecdotal Events Occurring in the Early History of Radiology in Berlin.
J Belg Soc Radiol
September 2024
Department of Medical Imaging, St. Nikolaus Hospital, Eupen, Belgium.
The authors define corrected dates of three remarkable events of early history of radiology in Berlin, which have been wrongly reported in the literature. Compiled evidence from contemporary newspaper publications demonstrates that Röntgen delivered his lecture to kaiser William II on 12 January 1896. Paul Spies gave a lecture on Röntgen rays to the Reichstag on 13 February 1896.
View Article and Find Full Text PDFStatement/comment to: Paul Spies (1862-1925) obtained the first publicly demonstrated X-ray in Berlin on January 20, 1896.
Rofo
September 2024
Historical Commission of the German Roentgen Society, Radiological Group Practice, Wuppertal, Germany.
Paul Spies (1862-1925) obtained the first publicly demonstrated X-ray in Berlin on January 20, 1896.
Rofo
September 2024
Medical Imaging, Liège University Hospital Sart Tilman Site, Liege, Belgium.
An exploratory research report on brain mineralization in postoperative delirium and cognitive decline.
Eur J Neurosci
May 2024
Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Delirium is a severe postoperative complication associated with poor overall and especially neurocognitive prognosis. Altered brain mineralization is found in neurodegenerative disorders but has not been studied in postoperative delirium and postoperative cognitive decline. We hypothesized that mineralization-related hypointensity in susceptibility-weighted magnetic resonance imaging (SWI) is associated with postoperative delirium and cognitive decline.
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