Accurate perception of biological tissues (BT) thickness is essential for preliminary evaluation of medical diagnosis and animal nutrition. However, traditional thickness measuring approaches of BT require complex operation, high-cost, and trigger biological stress response. Herein this study, an novel in vitro BT thickness measuring approach integrated with force test system (FST) and the discrete multiwavelet transform convolutional neural network (DMWA-CNN) prediction model based on deep learning are proposed. Simultaneously, several comprehensive experiments and model comparisons are conducted to demonstrate the superiority of the proposed approach. By establishing a DMWA-CNN demonstrates higher estimation accuracy than other traditional algorithm, achieving 100 % accuracy for artificial BT. Moreover, the experimental results indicate that proposed approach is robust to elastic modulus variation (E), external load variation (F), and small thickness differences (T). In addition, four kinds of the pork' thickness are experimentally measured, and the accuracy value is not less than 98.2 %. The thickness of BT determined using the FST and DMWA-CNN algorithm demonstrate potential application in the biomechanical parameter prediction.
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http://dx.doi.org/10.1016/j.compbiomed.2024.109181 | DOI Listing |
Int J Comput Assist Radiol Surg
January 2025
Advanced Medical Devices Laboratory, Kyushu University, Nishi-ku, Fukuoka, 819-0382, Japan.
Purpose: This paper presents a deep learning approach to recognize and predict surgical activity in robot-assisted minimally invasive surgery (RAMIS). Our primary objective is to deploy the developed model for implementing a real-time surgical risk monitoring system within the realm of RAMIS.
Methods: We propose a modified Transformer model with the architecture comprising no positional encoding, 5 fully connected layers, 1 encoder, and 3 decoders.
Bioinformatics
January 2025
Biocomputing Group, University of Bologna, Italy.
Motivation: The knowledge of protein stability upon residue variation is an important step for functional protein design and for understanding how protein variants can promote disease onset. Computational methods are important to complement experimental approaches and allow a fast screening of large datasets of variations.
Results: In this work we present DDGemb, a novel method combining protein language model embeddings and transformer architectures to predict protein ΔΔG upon both single- and multi-point variations.
J Orthop Surg Res
January 2025
Department of Human Anatomy, Graduate School, Inner Mongolia Medical University, Hohhot, 010010, Inner Mongolia, China.
Purpose: The study aimed to develop a deep learning model for rapid, automated measurement of full-spine X-rays in adolescents with Adolescent Idiopathic Scoliosis (AIS). A significant challenge in this field is the time-consuming nature of manual measurements and the inter-individual variability in these measurements. To address these challenges, we utilized RTMpose deep learning technology to automate the process.
View Article and Find Full Text PDFBMC Bioinformatics
January 2025
College of Artificial Intelligence, Nanjing Agricultural University, Weigang No.1, Nanjing, 210095, Jiangsu, China.
Antimicrobial peptides (AMPs) have been widely recognized as a promising solution to combat antimicrobial resistance of microorganisms due to the increasing abuse of antibiotics in medicine and agriculture around the globe. In this study, we propose UniAMP, a systematic prediction framework for discovering AMPs. We observe that feature vectors used in various existing studies constructed from peptide information, such as sequence, composition, and structure, can be augmented and even replaced by information inferred by deep learning models.
View Article and Find Full Text PDFCommun Biol
January 2025
Institute for Automation and Applied Informatics, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany.
Biomedical research increasingly relies on three-dimensional (3D) cell culture models and artificial-intelligence-based analysis can potentially facilitate a detailed and accurate feature extraction on a single-cell level. However, this requires for a precise segmentation of 3D cell datasets, which in turn demands high-quality ground truth for training. Manual annotation, the gold standard for ground truth data, is too time-consuming and thus not feasible for the generation of large 3D training datasets.
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