Optimizing surgical performance and safety in endoresection of uveal melanoma.

Retina

Ocular Oncology Unit, Department of Surgical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Published: September 2024

AI Article Synopsis

  • The study presents a standardized surgical technique for endoresection of uveal melanoma (UM) that aims to reduce the risk of serious complications, like fatal gas embolism.
  • The procedure was conducted on ten patients after proton beam radiotherapy and involved careful methods such as cauterizing vortex veins, vitrectomy, and using specialized fluids to stabilize the retina.
  • Results showed successful endoresection in all cases with no intraoperative complications, and follow-up indicated no signs of local recurrence or additional complications for the majority of patients.

Article Abstract

Purpose: To present a standardized surgical technique for endoresection of uveal melanoma (UM) minimizing the risk of serious adverse events, including fatal gas embolism.

Methods: Ten UM patients underwent endoresection following proton beam radiotherapy for radiotherapy-related vascular complications. Vortex veins located in correspondence of the tumor base had been cauterized at the time of tantalum markers placement. Endoresection was performed following complete 25G vitrectomy, endolaser and endodiathermy. The tumor was removed using a subretinal or transretinal approach depending on retinal infiltration. If needed, perfluorodecalin (PFD) was injected to stabilise the retina. Fluid-silicone oil (SO) or PFD-SO exchange was performed, avoiding air.

Results: Endoresection was successfully performed in all eyes with no intraoperative complications. Mean follow-up (FU) was 10.8 ± 3.2 months. One patient was enucleated due to neovascular glaucoma. At the last FU, the remaining patients had the eye preserved and no signs of local recurrence or neovascular glaucoma.

Conclusion: Our standardized surgical technique for UM endoresection appeared to be safe, minimizing the risk of serious intraoperative and postoperative adverse events.

Download full-text PDF

Source
http://dx.doi.org/10.1097/IAE.0000000000004273DOI Listing

Publication Analysis

Top Keywords

endoresection uveal
8
uveal melanoma
8
standardized surgical
8
surgical technique
8
technique endoresection
8
minimizing risk
8
risk serious
8
adverse events
8
endoresection performed
8
endoresection
6

Similar Publications

Clinical Features and Initial Management Outcomes of Uveal Melanomas in a Single Tertiary Center in Egypt.

Ocul Oncol Pathol

December 2024

Cairo University Ocular Oncology Service, Department of Ophthalmology, Kasr Al-Ainy School of Medicine, Cairo University, Cairo, Egypt.

Article Synopsis
  • The study focuses on the demographic, clinical, and management outcomes of patients with uveal melanoma at a tertiary center in Egypt over five years.
  • A total of 93 patients were treated, with most tumors being choroidal, and common treatments included brachytherapy and gamma knife radiosurgery, leading to a successful globe salvage rate of 84.62%.
  • The conclusion emphasizes the importance of timely referrals and proper assessments to improve treatment success and highlights the need for advanced tumor patients to consider enucleation to lower the risk of metastasis and mortality.
View Article and Find Full Text PDF

Optimizing surgical performance and safety in endoresection of uveal melanoma.

Retina

September 2024

Ocular Oncology Unit, Department of Surgical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Article Synopsis
  • The study presents a standardized surgical technique for endoresection of uveal melanoma (UM) that aims to reduce the risk of serious complications, like fatal gas embolism.
  • The procedure was conducted on ten patients after proton beam radiotherapy and involved careful methods such as cauterizing vortex veins, vitrectomy, and using specialized fluids to stabilize the retina.
  • Results showed successful endoresection in all cases with no intraoperative complications, and follow-up indicated no signs of local recurrence or additional complications for the majority of patients.
View Article and Find Full Text PDF
Article Synopsis
  • Uveal melanoma treatment has changed from removing the eye to less invasive methods, but complications can still happen after these treatments.
  • A team of experts reviewed research on how to use special eye surgery to fix problems caused by uveal melanoma.
  • Better tools and techniques in eye surgery now help doctors manage and prevent complications like bleeding and other serious issues.
View Article and Find Full Text PDF

Intraocular schwannoma: case series of 28 patients and literature review.

Eye (Lond)

May 2024

Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Purpose: Intraocular schwannoma is a rare tumour, which is often misdiagnosed. We presented the demographics and clinical characteristics of patients with intraocular schwannoma.

Methods: Retrospective case series were collected between May 2005 and July 2021 in Beijing Tongren Hospital.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!