AI Article Synopsis

  • Sulfanilic acid (SFA) crystal is a versatile material used in photonics and biomedical applications, and this article discusses the growth of a high-quality SFA single crystal using the slow evaporation solution method over 75 days.
  • The resulting transparent crystal, measuring 5 × 5 × 2 mm, underwent various characterizations such as Single Crystal XRD, FTIR, UV-Visible analysis, and Scanning Electron Microscopy to assess its structural and optical properties.
  • Notably, this study is the first to explore the cytotoxicity and larvicidal activity of SFA crystal, testing its efficacy against cancer cells and potential anti-malarial properties using the MTT Assay.

Article Abstract

Sulfanilic acid (SFA) crystal is well known as an effective material for photonic, electro-optical, harmonic generating and biomedical applications. A well-known nonlinear optical material, a high-quality SFA single crystal made utilizing the slow evaporation solution method (SEST) is the subject of this article. A 75 days development period yielded a transparent SFA single crystal measuring 5 × 5 × 2 mm. The grown crystal used for different characterizations like Single crystal XRD used to find out the cell parameters. Fourier transforms infrared utilized to identify the band assignments. UV-Visible analysis used to detect the absorbance of the crystal and it is utilized for optical application. Photoluminescence studies utilized to recognize the excitation and emission of the grown crystal. Fluorescence used for determining the crystallinity and purity of the sample. The quantitative analysis is verified by using Elemental Dispersive Analysis by X-Rays. Scanning Electron Microscopy utilized to identify the structural and morphological characteristics. To the best of our knowledge, this paper is the first to provide the generated crystal that was used to analyze cytotoxicity and larvacidal activity. Assessment of larvicidal activity was used to ascertain the anti-malarial efficacy. We tested the items on MCF7-Human Breast cancer cell line and MCF7 Vero cells using the MTT Assay to identify the molecular basis of their cytotoxicity in vitro. Biological and optical are two areas that could benefit from the created crystal.

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Source
http://dx.doi.org/10.1007/s12013-024-01547-8DOI Listing

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