AI Article Synopsis
- A study examined the effectiveness of combining contrast-enhanced MRI with CT in identifying whether ampullary strictures are malignant or benign, using 90 patients.
- The research involved three radiologists evaluating the diagnostic confidence of using just CT versus the combination of CT and MRI, with results analyzed for accuracy and agreement among observers.
- Findings indicated that adding MRI significantly improved the ability to predict malignancy and demonstrated higher diagnostic accuracy and interobserver agreement compared to CT alone.
Article Abstract
Purpose: To investigate the added value of using contrast-enhanced magnetic resonance imaging (MRI) in conjunction with contrast-enhanced computed tomography (CT) for differentiating malignant and benign ampullary strictures.
Materials And Methods: The present retrospective study included 90 patients with ampullary strictures who underwent preoperative contrast-enhanced CT and contrast-enhanced MRI at two tertiary institutions. The image sets (i.e., CT alone vs. combined CT and MRI) were evaluated by three abdominal radiologists, who used a five-point Likert scale to score their confidence for diagnosing malignancy in patients with ampullary strictures. Diagnostic accuracy was calculated using receiver-operating characteristic (ROC) curve analysis, sensitivity, specificity, and accuracy. Additionally, interobserver agreement regarding the scoring of potential malignancies of the ampullary strictures was assessed.
Results: The addition of contrast-enhanced MRI to contrast-enhanced CT showed a significant improvement in predicting malignant ampullary strictures in all three observers (p = 0.007, 0.001, and 0.002) using ROC curve analysis, and a significant improvement was observed in diagnostic sensitivity and accuracy for predicting malignancy (p = 0.016 and 0.029 for observer 1; p = 0.023 and 0.010 for observer 2; and p = 0.010 and 0.011 for observer 3). The interobserver agreement for the five-point scale in determining malignancies of the ampullary strictures was 0.86 for CT alone and 0.93 for the combined set of CT and MRI.
Conclusion: The addition of contrast-enhanced MRI to CT provided added value for differentiating malignant from benign ampullary strictures.
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| http://dx.doi.org/10.1007/s11604-024-01664-7 | DOI Listing |
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