Contraceptive Care in the Rheumatic Diseases: A Review.

J Clin Rheumatol

Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA.

Published: October 2024

AI Article Synopsis

  • - Contraception is crucial for individuals with rheumatic and musculoskeletal diseases (RMDs) to prevent undesired pregnancies and improve reproductive health, yet many do not receive tailored counseling regarding their options.
  • - The review highlights the availability of safe contraceptive methods for females with RMDs, emphasizing the need for specialized care for conditions like systemic lupus erythematosus and antiphospholipid syndrome due to their unique risks.
  • - There is a lack of contraceptive options for male patients, and while guidelines for adolescents with RMDs can follow those for adults, additional focus on protection against STIs is necessary. Future studies should explore how contraception affects RMD activity and associated side effects.

Article Abstract

Contraception can help individuals with rheumatic and musculoskeletal diseases (RMDs) to avoid undesired pregnancies and improve reproductive outcomes. Despite the importance of contraception in the care of females with RMDs, evidence suggests that many of these individuals do not receive consistent or disease-specific counseling regarding contraceptive options. This includes female patients receiving teratogenic prescriptions as part of the management of their RMDs, or who have severe disease activity that might culminate in adverse pregnancy and perinatal outcomes. Contraceptive counseling can help females with RMDs who wish to prevent pregnancy to select a contraceptive method that is best for them.We conducted a narrative review of the primary literature addressing reversible, prescription-based contraception for females with RMDs, framed by published guidelines on contraceptive safety. Many safe and effective contraceptive options are available for females with RMDs. Special considerations must be given to individuals with systemic lupus erythematosus, whose disease activity may be exacerbated by exogenous estrogen. Females with positive antiphospholipid antibodies should avoid estrogen-containing contraception due to an unacceptable risk of thrombosis and should conditionally avoid depot medroxyprogesterone acetate, which appears to have a prothrombotic signature. Limited contraceptive options are available to male patients. Contraceptive care for adolescents with RMDs can be extrapolated from guidelines written for adult patients, with the additional consideration of barrier protection for individuals at risk for sexually transmitted infections. Future research is needed to assess the effects of contraception use on rheumatic disease activity and side effects.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11462883PMC
http://dx.doi.org/10.1097/RHU.0000000000002124DOI Listing

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