A 57-year-old black male patient was admitted with flatulence and post-prandial fullness a month ago. No other gastrointestinal complaints. He had history of arterial hypertension, medicated with nifedipine 30mg/day and hydrochlorthiazide 50mg/day, and had been diagnosed and treated for malaria a week before admission. The patient reported frequent bathing in rivers and smoking habits since the age of 18, around a pack and a half a day. Abdominal ultrasound showed periportal fibrosis, without findings of portal hypertension. A rectal biopsy was performed with findings of Schistosome mansoni eggs on microscopy. This case illustrates a patient who was admitted due to dyspeptic syndrome, and during the study of his condition was found to have periportal fibrosis, which in a country endemic for Schistosomiasis such as Mozambique, this pathology must always be investigated. A history of bathing in rivers increases the chances of it being Schistosomiasis, confirmed by the demonstration of parasite eggs in a rectal biopsy. Treatment with prazinquantel was done at a dose of 40 mg/kg and outpatient follow-up was scheduled for six months.
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http://dx.doi.org/10.17235/reed.2024.10768/2024 | DOI Listing |
J Assoc Physicians India
December 2024
Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Disorders of gut-brain interaction (DGBI), formerly known as functional bowel disorders, encompass a diverse array of conditions and symptoms that may manifest in different parts of the gastrointestinal tract. Some of the most prevalent DGBIs include functional dyspepsia, irritable bowel syndrome, functional constipation, functional diarrhea, and functional bloating and distension. Around 80% of patients with dyspepsia have no identifiable organic cause and are labeled as functional dyspepsia.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Endocrinology Research Centre, Moscow 117292, Russia.
GATA6 syndrome is a rare monogenic disorder caused by heterozygous variants in the gene , which controls the early embryonic differentiation of germ layers and the development of different organs. We present the results of the 7-year follow-up of a child with this syndrome as well as the following conditions: diabetes mellitus, exocrine pancreatic insufficiency, gallbladder atresia, and congenital heart disease (CHD). At birth, the patient was diagnosed with neonatal diabetes mellitus (NDM) associated with heart (mitral valve prolapse) and gastrointestinal abnormalities (gallbladder atresia).
View Article and Find Full Text PDFBMC Gastroenterol
November 2024
Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, Hubei Province, China.
Background: The Rome IV criteria for functional dyspepsia (FD) has strict requirements for symptom frequency and onset duration, making it difficult for patients to meet these criteria in clinical practice. This study aimed to investigate the impact of relaxing the Rome IV criteria on the diagnosis and symptom pattern of FD.
Methods: A cross-sectional, multi-center study was conducted involving 2935 consecutive broadly defined FD patients without positive findings on upper gastrointestinal endoscopy or routine examinations.
Rev Esp Enferm Dig
December 2024
Gastroenterology, Hospital Central de Maputo.
A 57-year-old black male patient was admitted with flatulence and post-prandial fullness a month ago. No other gastrointestinal complaints. He had history of arterial hypertension, medicated with nifedipine 30mg/day and hydrochlorthiazide 50mg/day, and had been diagnosed and treated for malaria a week before admission.
View Article and Find Full Text PDFGastroenterol Hepatol (N Y)
August 2024
Division of Gastroenterology & Hepatology, Mayo Clinic Jacksonville, Jacksonville, Florida.
Leaky gut syndrome is a condition widely popularized in the lay literature, although it is not currently accepted as a formal medical diagnosis. Multiple gastrointestinal symptoms are ascribed to leaky gut syndrome, including diarrhea, bloating, distension, abdominal pain, and dyspeptic symptoms of early satiety, nausea, and postprandial fullness. The etiology and pathophysiology of leaky gut syndrome are multifactorial; a preceding gastrointestinal infection, inflammatory bowel disease, and certain medications may be relevant factors in some patients.
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