AI Article Synopsis
- Pancreatogenic diabetes mellitus is becoming more prominent due to its high rates of occurrence, complications, and mortality, with glycemic variability (GV) being a key risk factor.
- Effective management of GV is essential for preventing this type of diabetes and improving patient outcomes, yet many patients receive inadequate or potentially harmful medications.
- This study aims to explore the connection between GV and pancreatogenic diabetes, investigate underlying mechanisms, and offer lifestyle tips and better medication choices for managing GV in affected patients.
Article Abstract
In recent years, pancreatogenic diabetes mellitus has garnered significant attention due to its high incidence, complications, and mortality rates. Glycemic variability (GV) can increase the risk of pancreatogenic diabetes mellitus and its associated complications; however, the precise mechanism remains unclear. The effective control of GV is crucial for preventing the onset of pancreatic diabetes mellitus and improving prognosis. Both diet and antidiabetic medications have substantial effects on GV. However, many patients are prescribed suboptimal or even harmful drugs. Therefore, to provide a comprehensive treatment basis for clinicians to prevent and treat pancreatogenic diabetes mellitus, this study aimed to elucidate the relationship between GV and pancreatogenic diabetes mellitus; investigate the potential mechanisms (such as oxidative stress, inflammatory response, insulin resistance, and lipid metabolism disorders); provide lifestyle guidance; and recommend drug selections to reduce the GV in patients with pancreatogenic diabetes mellitus.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11423834 | PMC |
| http://dx.doi.org/10.2147/IJGM.S477497 | DOI Listing |
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