AI Article Synopsis

  • Coronary artery spasms can cause serious heart issues like ischaemia and infarction, particularly in younger individuals, affecting both genders equally.
  • A case study highlighted two sisters who suffered heart attacks during menstruation due to catamenial coronary spasms, leading to significant complications for one sister, including heart failure and a heart transplant.
  • Increased awareness and understanding of catamenial coronary spasms, particularly their link to fluctuating hormone levels, is crucial for proper diagnosis and treatment involving medications that promote blood vessel dilation.

Article Abstract

Coronary artery spasms represent important causes of myocardial ischaemia and infarction in patients with non-obstructive coronary artery disease. They are notably seen in younger people and occur almost equally in men and women. Besides traditional risk factors (ie, smoking), female hormones might also play a role.We report of two young sisters who presented with myocardial infarction caused by catamenial coronary spasms (CS), that is, during menstruation. In one of these women, this resulted in heart failure with a severely reduced ejection fraction and ultimately a heart transplant because of intractable ventricular arrhythmias.CS might result from changing hormone levels (especially oestrogen) during menstruation. Increased awareness of the occurrence of catamenial CS is essential for diagnosis and consequent treatment with coronary vasodilators and/or specific oestrogen/progesterone regimens.

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http://dx.doi.org/10.1136/bcr-2024-260281DOI Listing

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