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Efficacy and safety of indocyanine green fluorescence navigation versus conventional laparoscopic hepatectomy for hepatocellular carcinoma: a systematic review and meta-analysis.
Surg Endosc
January 2025
Department of Hepatobiliary and Pancreatic SurgeryIII, the Second Affiliated Hospital of Kunming Medical University, Kunming, 650101, China.
Background: Indocyanine green (ICG) fluorescence imaging technology is increasingly widely used in laparoscopic hepatectomy. However, previous studies have produced conflicting results regarding whether it is truly superior to traditional laparoscopic hepatectomy. This study investigated the clinical effect of laparoscopic hepatectomy for hepatocellular carcinoma (HCC) using ICG imaging technology.
View Article and Find Full Text PDFComparison of smart burs and chemo-mechanical caries removal systems in primary molars - A systematic review and meta-analysis.
J Indian Soc Pedod Prev Dent
October 2024
Department of Pediatric and Preventive Dentistry, D. Y. Patil University School of Dentistry, Navi Mumbai, Maharashtra, India.
Article Synopsis
- Smart burs and chemo-mechanical caries removal (CMCR) systems are alternative techniques for cavity preparation, but existing studies show mixed results regarding their efficacy, efficiency, and patient comfort.
- This systematic review analyzed in vivo studies comparing these methods, excluding lower-quality sources and conducting a thorough risk of bias assessment on the included studies.
- The analysis revealed that, although 154 studies were initially reviewed, only a few were suitable for meta-analysis, showing no significant difference in clinical efficacy between CMCR systems and smart burs.
Clinical features, treatment, and prognosis of pembrolizumab -induced Stevens-Johnson syndrome / toxic epidermal necrolysis.
Invest New Drugs
January 2025
College of Pharmacy, Changsha Medical University, No. 1501 Leifeng Avenue, Xiangjiang New District, Changsha, Hunan, 410219, China.
The understanding of pembrolizumab-induced Stevens-Johnson syndrome (SJS) /toxic epidermal necrolysis (TEN) primarily derives from case reports, leaving specific clinical features largely unknown. This study aims to investigate the clinical characteristics associated with pembrolizumab-induced SJS/TEN and to encourage the judicious use of pembrolizumab. Retrieve reports on pembrolizumab induced SJS/TEN before September 30, 2024 for retrospective analysis.
View Article and Find Full Text PDFRecombinant vs Egg-Based Quadrivalent Influenza Vaccination for Nursing Home Residents: A Cluster Randomized Trial.
JAMA Netw Open
January 2025
Transformative Health Systems Research to Improve Veteran Equity and Independence Center of Innovation, Veterans Affairs Providence Health Care System, Providence, Rhode Island.
Article Synopsis
- Influenza vaccination is crucial to prevent illness and death in nursing home residents, and this study compares the effectiveness of recombinant influenza vaccine versus standard-dose vaccines in this population.
- Conducted across two influenza seasons, the study randomized nursing homes to administer either the recombinant quadrivalent vaccine or the standard vaccine, focusing on residents aged 65 and older.
- The main outcome measured was respiratory-related hospitalization rates, while secondary outcomes included overall mortality and hospitalization for any reason, with a substantial sample size of over 144,000 observations.
Molecular classification of endometrial cancer: Impact on adjuvant treatment planning.
Cytojournal
November 2024
1st Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Papageorgiou Hospital, Thessaloniki, Greece.
Objective: The traditional histopathological analysis of endometrial cancer (EC) is the main risk group classification tool (low, intermediate, high-intermediate, and high) for the implementation of adjuvant treatment. The International Federation of Gynecology and Obstetrics staging system of EC has incorporated a new molecular classification that serves as a new triage tool for optimal treatment planning for these patients. Our study aimed to investigate the prognostic role of the new molecular classification in EC.
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