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Recent updates in the WHO guidelines for malaria case management.
Sudan J Paediatr
January 2024
Independent Consultant, Lawrenceville, Georgia, USA.
This is a brief review that highlights recent updates in malaria case management. Recent WHO revisions include a new artemisinin-based molecule (artesunate-pyronaridine), revising the recommendations for treating uncomplicated malaria during the first trimester of pregnancy and optimising primaquine dose to prevent relapses. The review also highlights innovative ideas to improve the implementation of guidelines for severe malaria and pre-referral treatment with rectal artesunate.
View Article and Find Full Text PDFEffect of Health Education Intervention on Knowledge and Adherence to Intermittent Preventive Treatment of Malaria in Pregnancy Among Women.
Healthcare (Basel)
January 2025
Department of Nursing Sciences, Faculty of Basic Medical and Health Sciences, Walter Sisulu University, Nelson Mandela Drive Campus, Mthatha 5117, South Africa.
Malaria in pregnancy is a global health problem because it causes anemia in the mother and may result in abortion, stillbirth, uterine growth retardation, and low birth weight in the newborn. The purpose of this study was to assess the effects of HEI on knowledge and adherence to intermittent preventive treatment of malaria among pregnant women at secondary health facilities in Benue State, Nigeria. This quasi-experimental study included pre-, intervention, and post-intervention.
View Article and Find Full Text PDFPrevalence, characteristics, and treatment outcome of congenital malaria in Nigeria: a systematic review.
Malar J
January 2025
Department of Medicine and Surgery, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
Background: Congenital malaria remains a significant public health challenge in Nigeria, particularly in regions with high malaria endemicity. The increased vertical transmission of malaria is partly associated with the high susceptibility of women to malaria during pregnancy. This systematic review aimed to assess the prevalence, characteristics, and treatment outcomes of congenital malaria in Nigeria.
View Article and Find Full Text PDFComparative performance of microscopy, rapid diagnostic tests, and multiplex real-time PCR for detection of malaria parasites among pregnant women in northwest Ethiopia.
Malar J
January 2025
Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Article Synopsis
- Evaluating diagnostic methods for malaria in pregnancy is crucial due to the risk of false negatives from microscopy and RDT, which can lead to health complications.
- A study collected blood samples from 835 pregnant women in northwest Ethiopia to compare the effectiveness of microscopy, RDT, and multiplex qPCR in diagnosing Plasmodium infections.
- Results showed that multiplex qPCR had the highest sensitivity (100%) compared to microscopy (73.8% for peripheral blood) and RDT (67.6% for peripheral blood), highlighting the need for improved diagnostic strategies in pregnant women.
Dynamics of Persistent Submicroscopic and Microscopic in Pregnant Women Under Intermittent Preventive Treatment: A Study Cohort in Benin.
Open Forum Infect Dis
January 2025
UMR261 MERIT, Université Paris Cité, IRD, Paris, France.
Background: Malaria infections in pregnancy are a major cause of maternal morbidity and neonatal mortality in sub-Saharan Africa. A high proportion of these infections are submicroscopic, which are usually asymptomatic and therefore untreated during pregnancy. Intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) aims to prevent and treat all potential infections whether submicroscopic or not.
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