Recent advances in pathogenesis, diagnosis, and therapeutic approaches for digestive system involvement in systemic lupus erythematosus.

J Dig Dis

Department of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.

Published: July 2024

AI Article Synopsis

  • Systemic lupus erythematosus (SLE) is an autoimmune disease where the body produces autoantibodies, leading to various symptoms, including issues with the digestive system.
  • Patients with digestive involvement may have unusual symptoms that can make diagnosis and treatment challenging, risking serious health complications.
  • The review discusses the causes, symptoms, diagnosis, and treatment options for gastrointestinal issues associated with SLE, emphasizing the need for careful monitoring by healthcare professionals.

Article Abstract

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the presence of large amounts of autoantibodies and immune complex formation. Because of their atypical clinical symptoms, SLE patients with digestive system involvement may not be recognized or treated precisely and extensively. Clinicians should pay close attention to SLE with digestive system involvement, as these conditions can easily worsen the condition and possibly endanger the patient's life. In this review we summarized the pathogenesis, pathological characteristics, clinical manifestations, diagnosis, and therapies for digestive system involvement in SLE.

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http://dx.doi.org/10.1111/1751-2980.13307DOI Listing

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