AI Article Synopsis
- - Pseudoxanthoma elasticum (PXE) is a rare connective tissue disease that impacts the formation of elastic fibers, which can complicate surgical procedures like revascularization in affected patients.
- - A notable case involved a 43-year-old man with PXE and coronary artery disease who had successful off-pump coronary artery bypass graft (CABG) surgery using the left internal mammary artery (LIMA) to the left anterior descending (LAD) artery.
- - This case represents the first occurrence of off-pump surgery for PXE in the UK and the second recorded in medical literature, suggesting a need for further research to establish standardized surgical practices for PXE patients.
Article Abstract
Pseudoxanthoma elasticum is a rare connective tissue disease which affects the synthesis of the elastic fibres. It is an area of uncertainty for patients affected by this disease requiring surgical revascularization. We present a case report of a 43-year-old gentleman was known to have pseudoxanthoma elasticum syndrome (PXE) and coronary artery disease. He underwent successful off pump LIMA to LAD. Interestingly, this is the first case in UK and second one in the literature managed with an off-pump strategy. The predilection of the histopathological changes in PXE patients, should not prevent the routine use in of the left internal mammary artery as a standard conduit in CABG. Further studies are required to standardize the practice for surgical revascularization in the patients with PXE.
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| http://dx.doi.org/10.1177/02676591241288180 | DOI Listing |
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