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Evaluation of the Effects of Sedation and Anesthesia on Total Lung Volume and Attenuation in Rabbit Lung CT Exams.
Animals (Basel)
December 2024
Veterinary Teaching Hospital, University of Trás-os-Montes e Alto Douro, 5000-801 Vila Real, Portugal.
Respiratory disease is common in rabbits, but subclinical conditions can be challenging to diagnose and may cause respiratory problems during anesthesia. CT is the preferred method for diagnosing lung diseases, but anesthesia can alter lung volume and cause lung lobe collapse. In this study, seventeen healthy 5-month-old male New Zealand white rabbits underwent thoracic CT scans under different conditions.
View Article and Find Full Text PDFA randomized controlled trial investigating the impact of early goal-directed sedation dominated by dexmedetomidine on cerebral oxygen metabolism and inflammatory mediators in patients with severe brain injury.
Neurol Sci
December 2024
Department of Surgical Intensive Care Unit, Yantai Mountain Hospital Affiliated to Binzhou Medical College, No.10087, Keji Avenue, Yantai, Shandong, 264000, China.
Objective: The aim of this study is to assess the neuroprotective efficacy of early goal-directed sedation (EGDS) primarily governed by dexmedetomidine in patients experiencing severe traumatic brain injury, and to elucidate its potential underlying mechanisms.
Data And Methods: All participants were randomly allocated into two groups: the experimental group-dexmedetomidine-dominated EGDS group (group D, n = 30) and the control group-the standard propofol sedation group (group P, n = 30). Patients in the experimental group received sedation primarily with dexmedetomidine, while those in the control group received propofol sedation.
The effect of intravenous hydromorphone alone or in combination with midazolam or dexmedetomidine on intraocular pressure in dogs.
Vet Anaesth Analg
November 2024
Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA, USA.
Objective: To evaluate the effect of intravenous (IV) hydromorphone alone or in combination with midazolam or dexmedetomidine on intraocular pressure (IOP) in dogs.
Study Design: Prospective, randomized, blinded, crossover study.
Animals: A group of seven healthy, ophthalmologically normal, adult Beagle dogs.
The Effect of Dexmedetomidine on Inflammatory Factors and Clinical Outcomes in Patients With Septic Shock: A Randomized Clinical Trial.
Clin Ther
December 2024
Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Sari Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Purpose: Dexmedetomidine is a sedative-analgesic that is widely used in sepsis. However, its effect on septic shock remains unclear. This study aimed to investigate dexmedetomidine's effect on inflammatory biomarkers in septic shock.
View Article and Find Full Text PDFAn evaluation of haemodynamic responses to tracheal intubation following intravenous dexmedetomidine and fentanyl in patients undergoing laparoscopic cholecystectomy.
Niger Med J
November 2024
Department of Anaesthesia, Eternal Heart Care Centre and Research Institute, Jaipur, India.
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