Atmospheric methane concentrations rose rapidly over the past decade and surged in 2020-2022 but the causes have been unclear. We find from inverse analysis of GOSAT satellite observations that emissions from the wet tropics drove the 2010-2019 increase and the subsequent 2020-2022 surge, while emissions from northern mid-latitudes decreased. The 2020-2022 surge is principally contributed by emissions in Equatorial Asia (43%) and Africa (30%). Wetlands are the major drivers of the 2020-2022 emission increases in Africa and Equatorial Asia because of tropical inundation associated with La Niña conditions, consistent with trends in the GRACE terrestrial water storage data. In contrast, emissions from major anthropogenic emitters such as the United States, Russia, and China are relatively flat over 2010-2022. Concentrations of tropospheric OH (the main methane sink) show no long-term trend over 2010-2022 but a decrease over 2020-2022 that contributed to the methane surge.
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http://dx.doi.org/10.1073/pnas.2402730121 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Department of Signaling and Gene Expression, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.
is one of the three most frequently mutated genes in age-related clonal hematopoiesis (CH), alongside and (. CH can progress to myeloid malignancies including chronic monomyelocytic leukemia (CMML) and is also strongly associated with inflammatory cardiovascular disease and all-cause mortality in humans. DNMT3A and TET2 regulate DNA methylation and demethylation pathways, respectively, and loss-of-function mutations in these genes reduce DNA methylation in heterochromatin, allowing derepression of silenced elements in heterochromatin.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2025
The Cyprus Institute, Climate and Atmosphere Research Center, 2121, Nicosia, Cyprus.
The production of nitrogen oxides (NO = NO + NO ) is substantial in urban areas and from fossil fuel-fired power plants, causing both local and regional pollution, with severe consequences for human health. To estimate their emissions and implement air quality policies, authorities often rely on reported emission inventories. The island of Cyprus is de facto divided into two different political entities, and as a result, such emissions inventories are not systematically available for the whole island.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167-RID-AGE, DISTALZ, Lille, France.
Background: BIN1 is a major susceptibility gene for AD and BIN1 protein interacts with Tau. However, the contribution of BIN1 and its isoforms to AD pathogenesis remains unclear. We recently described that human BIN1 isoform1 (BIN1iso1) induces an accumulation of early endosome vesicles leading to neurodegeneration in Drosophila retina and that the early endosome size regulation was conserved in human induced neurons.
View Article and Find Full Text PDFSci Rep
January 2025
Environment and Sustainability Institute, University of Exeter, Penryn, TR10 9FE, UK.
Understanding the spatial ecology of commercially exploited species is vital for their conservation. Atlantic bluefin tuna (Thunnus thynnus, ABT) are increasingly observed in northeast Atlantic waters, yet knowledge of these individuals' spatial ecology remains limited. We investigate the horizontal and vertical habitat use of ABT (158 to 241 cm curved fork length; CFL) tracked from waters off the United Kingdom (UK) using pop-up satellite archival tags (n = 63).
View Article and Find Full Text PDFNat Commun
January 2025
Department of Earth Observation Science, Faculty of Geo-information Science and Earth Observation (ITC), University of Twente, Overijssel, The Netherlands.
Accurate global glacier mapping is critical for understanding climate change impacts. Despite its importance, automated glacier mapping at a global scale remains largely unexplored. Here we address this gap and propose Glacier-VisionTransformer-U-Net (GlaViTU), a convolutional-transformer deep learning model, and five strategies for multitemporal global-scale glacier mapping using open satellite imagery.
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