A pure amnesic syndrome of 21 months' duration occurred in a 36-year-old man following a transient confusional state. The patient died of Hodgkin's disease. At postmortem examination, bilateral and symmetrical neuronal loss, without inflammatory changes, was restricted to the hippocampus and amygdaloid bodies.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/ana.410180307 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A comprehensive review of ethnomedicinal approaches, phytochemical analysis, and pharmacological potential of L.
Front Pharmacol
March 2024
Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Plants, renowned for their rich reservoir of metabolites, play a pivotal role in addressing health-related issues. The Verbenaceae family stands out, showcasing immense potential in preventing and treating chronic diseases. L.
View Article and Find Full Text PDFEffects of Jacquem on Memory Deficits and Brain Oxidative Stress in Streptozotocin-Induced Diabetic Mice.
Molecules
April 2022
Department of Biological Sciences, National University of Medical Sciences, Rawalpindi 46000, Punjab, Pakistan.
Different species of have been reported to have therapeutic potential in treating various health disorders, including diabetes and memory dysfunction. The present study was planned to evaluate the effects of Jacquem crude extract and its subfractions as antiamnesic agents in streptozotocin-induced (STZ) diabetic mice. The in vivo behavioral studies were performed using the Y Maze test and novel object recognition test (NORT) test at doses of 100 and 200 mg/kg of crude extract and 75 and 150 mg/kg of fractions.
View Article and Find Full Text PDFBeetroot supplemented diet exhibit anti-amnesic effect via modulation of cholinesterases, purinergic enzymes, monoamine oxidase and attenuation of redox imbalance in the brain of scopolamine treated male rats.
Nutr Neurosci
May 2022
Functional Food and Nutraceutical Unit, Department of Biochemistry, Federal University of Technology, Akure.
Objectives: , commonly known as beetroot, is a vegetable that contains red pigment and rich in betalains, phenolic acids, and flavonoids. This study was designed to assess the effect of beetroot supplemented diet (BRSD) on cognitive function and altered neurochemicals associated with Alzheimer's disease (AD) in the brain of rats treated with scopolamine (SCOP).
Methods: Rats were fed with BRSD (2 and 4%) for 14 days and administered with 2 mg/kg of SCOP intraperitoneally on the last day.
Does amnesia specifically predict Alzheimer's pathology? A neuropathological study.
Neurobiol Aging
November 2020
Univ Lille, Lille Neuroscience & Cognition (Inserm UMRS1172) Degenerative and Vascular Cognitive Disorders, CHU Lille, Laboratory of Excellence Distalz (Development of Innovative Strategies for a Transdisciplinary approach to ALZheimer's disease), Lille, France.
Amnesia is a key component of Alzheimer's disease (AD) and the most important feature of its clinical diagnosis but its specificity has recently been challenged. This study investigated the ability of amnesia to predict AD in a clinicopathological dementia series. Ninety-one patients to which free and cued verbal memory assessment was administered during early cognitive decline, were followed until autopsy.
View Article and Find Full Text PDFBrain targeting of resveratrol through intranasal lipid vesicles labelled with gold nanoparticles: evaluation and bioaccumulation investigation using computed tomography and histopathological examination.
J Drug Target
December 2019
Department of Pharmaceutics and Industrial Pharmacy Faculty of Pharmacy, Nahda University (NUB), Beni-Suef , Egypt.
Resveratrol is a promising neuroprotective agent against neurodegenerative disorders such as Alzheimer's disease. Resveratrol-loaded transferosomes and nanoemulsions were developed and labelled with gold nanoparticles (GNPs). The water maze test was utilised to identify the effect on spatial memory recovery.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!