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Calcium oscillations and mitochondrial enzymes in stem cells. | LitMetric

Calcium oscillations and mitochondrial enzymes in stem cells.

Regen Ther

Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo 157-8535, Japan.

Published: June 2024

AI Article Synopsis

  • Calcium oscillations are rhythmic changes in calcium ion levels inside cells, which are crucial for various cellular functions.
  • These oscillations influence key biological events like neuron formation and stem cell growth, and their patterns vary by cell type.
  • Understanding and regulating these calcium fluctuations is important, as disruptions can lead to health issues, including neurodegenerative diseases.

Article Abstract

Calcium oscillations are rhythmic fluctuations of the intracellular concentration of calcium ions (Ca). As Ca evokes various cellular processes, its intracellular concentration is tightly regulated. Ca oscillations control biological events, including neuronal differentiation and proliferation of mesenchymal stem cells. The frequency and pattern of Ca oscillations depend on cell type. Researchers have studied Ca oscillations to better understand how cells communicate and regulate physiological processes. Dysregulation of Ca oscillations causes health problems, such as neurodegenerative disorders. This review discusses the potential functions of Ca oscillations in stem cells.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419779PMC
http://dx.doi.org/10.1016/j.reth.2024.09.002DOI Listing

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