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| http://dx.doi.org/10.1073/pnas.2416360121 | DOI Listing |
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Castanet: a pipeline for rapid analysis of targeted multi-pathogen genomic data.
Bioinformatics
October 2024
Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxfordshire OX1 3SY, United Kingdom.
Motivation: Target enrichment strategies generate genomic data from multiple pathogens in a single process, greatly improving sensitivity over metagenomic sequencing and enabling cost-effective, high-throughput surveillance and clinical applications. However, uptake by research and clinical laboratories is constrained by an absence of computational tools that are specifically designed for the analysis of multi-pathogen enrichment sequence data. Here we present an analysis pipeline, Castanet, for use with multi-pathogen enrichment sequencing data.
View Article and Find Full Text PDFSecret code: Encoding promoters by synonymous codons.
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College of Horticulture and Landscape, Yangzhou University, Yangzhou, China.
Old trees are remarkable for their ability to endure for centuries or even millennia, acting as recordkeepers of historical climate and custodians of genetic diversity. The secret to their longevity has long been a subject of fascination. Despite the challenges associated with studying old trees, such as massive size, slow growth rate, long lifespan and often remote habitat, accumulating studies have investigated the mechanisms underlying tree aging and longevity over the past decade.
View Article and Find Full Text PDFBackground: In the Healthcare (HC) sector, the usage of Wireless Sensor Healthcare Networks (WSHN) is attaining specific importance. The sensor device is implanted into the patient's body, and the sensed health information of patients is transformed via data aggregating devices like mobile devices, cameras, and so on, to the doctors. Thus, the early signs of diseases are identified, and remote monitoring of the patient's health is carried out by the physician on time.
View Article and Find Full Text PDFLinear Codes Constructed from Two Weakly Regular Plateaued Functions with Index ( - 1)/2.
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School of Mathematics, Sun Yat-sen University, Guangzhou 510275, China.
Linear codes are the most important family of codes in cryptography and coding theory. Some codes only have a few weights and are widely used in many areas, such as authentication codes, secret sharing schemes and strongly regular graphs. By setting p≡1(mod4), we constructed an infinite family of linear codes using two distinct weakly regular unbalanced (and balanced) plateaued functions with index (p-1)/2.
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