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Retrospective analysis of 80 patients diagnosed with reversible cerebral vasoconstriction syndrome in the Helsinki Metropolitan Area.
Eur J Neurol
February 2025
Neurology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Background And Purpose: Up to 80% of patients diagnosed with reversible cerebral vasoconstriction syndrome (RCVS) experience complications such as ischaemic stroke, intracerebral or subarachnoid haemorrhage or posterior reversible encephalopathy syndrome. The aim was to evaluate the incidence of complications in patients diagnosed with RCVS in our clinic.
Patients And Methods: All adult patients (age >16 years) diagnosed with RCVS at the Helsinki University Central Hospital during the period between 1 January 2016 and 31 December 2022 were retrospectively identified.
Abnormal skeletal muscle and myocardial vasoreactivity manifests prior to heart failure in a diabetic cardiomyopathy rat model.
Discov Med (Cham)
January 2025
Institute of Biomedical Engineering, University of Toronto, Toronto, ON Canada.
Background: Microvascular dysfunction (MVD) is a recognized sign of disease in heart failure progression. Intact blood vessels exhibit abnormal vasoreactivity in early stage, subsequently deteriorating to rarefaction and reduced perfusion. In managing heart failure with preserved ejection fraction (HFpEF), earlier diagnosis is key to improving management.
View Article and Find Full Text PDFReversible Cerebral Vasoconstriction Syndrome for the Internist-A Narrative Review.
Am J Med
November 2024
Department of Neurology, Massachusetts General Hospital, Boston, Mass.
Reversible cerebral vasoconstriction syndrome is a common, increasingly recognized cause of thunderclap headache. Most patients have some type of trigger that precedes the onset (e.g.
View Article and Find Full Text PDFEarlier vasoconstriction in females than males with matched body size and composition in neutral-cool conditions.
Proc Natl Acad Sci U S A
October 2024
Centre for Molecular Biosciences and Non-Communicable Diseases, School of Safety Science & Engineering, Xi'an University of Science and Technology, Xi'an 710054, China.
The physiological basis for individualized oxygenation targets in critically ill patients with circulatory shock.
Intensive Care Med Exp
August 2024
Institute of Intensive Care Medicine, University Hospital of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
Background: Circulatory shock, defined as decreased tissue perfusion, leading to inadequate oxygen delivery to meet cellular metabolic demands, remains a common condition with high morbidity and mortality. Rapid restitution and restoration of adequate tissue perfusion are the main treatment goals. To achieve this, current hemodynamic strategies focus on adjusting global physiological variables such as cardiac output (CO), hemoglobin (Hb) concentration, and arterial hemoglobin oxygen saturation (SaO).
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