Objective: Attention-deficit hyperactivity disorder (ADHD) increases the risk for comorbid psychiatric and substance use disorders. This study examined the prevalence of ADHD in residential addiction treatment and the prevalence of monosubstance, comorbid substance, and polysubstance use disorders (PUD) as a function of ADHD status.
Method: All adults admitted to residential substance use disorder treatment center in South Dakota during November 2021 to June 2022 were included (N= 55). The participants underwent a clinical interview and objective assessment to determine ADHD status. The participants were also administered ADHD questionnaire developed by investigators to assess ADHD history and treatment. SAS statistical software using an α level of 0.05 was used for all analyses.
Results: Almost half, 25 of the total 55 participants, had ADHD (45%). A quarter (n=14) of participants were diagnosed with ADHD during childhood. A fifth (n=11) of participants were diagnosed with ADHD during this study. Thirty participants (54%) were not found to have ADHD. A majority of ADHD patients (n=21; 84%) were diagnosed with PUD. Participants with ADHD had a higher prevalence of PUD (p=0.054) compared to participants without ADHD. Approximately a quarter of patients with alcohol use disorder and three-quarters of patients with methamphetamine use disorder had ADHD.
Conclusions: ADHD and substance use disorders have notable comorbidity. This study demonstrates a high prevalence of ADHD in populations with substance use disorder. The presence of ADHD may be a risk factor for PUD.
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Introduction: Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder among children and adolescents. The disorder negatively influences their academic performance and social relations, and their quality of life (QoL) is lower than that of peers without ADHD. The majority of children and adolescents with ADHD are treated with medication that potentially has an insufficient effect or frequently occurring adverse events.
View Article and Find Full Text PDFPsychol Med
January 2025
Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Functional & Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu, China.
Background: Psychostimulants and nonstimulants have partially overlapping pharmacological targets on attention-deficit/hyperactivity disorder (ADHD), but whether their neuroimaging underpinnings differ is elusive. We aimed to identify overlapping and medication-specific brain functional mechanisms of psychostimulants and nonstimulants on ADHD.
Methods: After a systematic literature search and database construction, the imputed maps of separate and pooled neuropharmacological mechanisms were meta-analyzed by Seed-based Mapping toolbox, followed by large-scale network analysis to uncover potential coactivation patterns and meta-regression analysis to examine the modulatory effects of age and sex.
Int J Behav Nutr Phys Act
January 2025
Department of Sports Science and Physical Education, The Chinese University of Hong Kong, Hong Kong SAR, China.
Background: Physical activity (PA) interventions have been shown to yield positive effects on cognitive functions. However, it is unclear which type of PA intervention is the most effective in children and adolescents with Neurodevelopmental Disorders (NDDs). This study aimed to compare the effectiveness of different types of PA interventions on cognitive functions in children and adolescents with NDDs, with additional analyses examining intervention effects across specific NDD types including attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD).
View Article and Find Full Text PDFAnn Gen Psychiatry
January 2025
Department of Psychiatry and Psychotherapy, Semmelweis University, 1083 Balassa utca 6, Budapest, Hungary.
Background: Increased levels of emotion dysregulation and impulsive behavior are overlapping symptoms in adult Attention-Deficit/Hyperactivity Disorder (aADHD) and Borderline Personality Disorder (BPD), both symptom domains reflecting on inhibitory control, although from different angles. Our aims were to describe their differences in the above conditions, investigate their associations with childhood traumatization, and to explore the potential mediation of emotion dysregulation and impulsivity between childhood traumas and personality functioning.
Methods: Young adults between 18 and 36 years diagnosed with aADHD (n = 100) and BPD (n = 63) were investigated with structured clinical interviews, while age-matched healthy controls (n = 100) were screened for psychiatric disorders.
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