AI Article Synopsis
- The study investigates the clinical features, causes, and outcomes of meningitis and encephalitis in adults in Saudi Arabia, aiming to fill a knowledge gap about these serious CNS infections.* -
- Conducted as a retrospective single-center study from March 2016 to May 2022, it revealed that most infections were caused by unidentified pathogens and that a significant portion of patients had received antibiotics before lumbar puncture.* -
- The findings emphasized the need for timely treatment according to guidelines and suggested the creation of national biobanks to improve the understanding of meningitis and encephalitis in Saudi Arabia.*
Article Abstract
(1) Background: Central nervous system (CNS) infections, including meningitis and encephalitis, are serious conditions which are associated with high morbidity and mortality. This study aims to identify the clinical manifestations, etiologies, and outcomes of meningitis and encephalitis in adult patients in Saudi Arabia, addressing the current gap in understanding these conditions within this population. (2) Methods: This is a single-center retrospective study which included all adult patients diagnosed with meningitis and encephalitis from March 2016 to May 2022. (3) Results: This study found that most cases of meningitis and encephalitis occurred due to unknown pathogens. Pretreatment with antibiotics prior to lumbar puncture (LP) was found in 71.2% of patients with meningitis. Altered mental status and seizures were common presenting symptoms among patients with encephalitis while altered mental status and fever were common among patients with meningitis. (4) Conclusions: Adherence to guidelines in treating meningitis and encephalitis and performing LPs in a timely manner are important. Establishing national biobanks with biological samples from patients suspected of having meningitis or encephalitis will significantly enhance our understanding of these conditions in Saudi Arabia.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417761 | PMC |
| http://dx.doi.org/10.3390/neurolint16050073 | DOI Listing |
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