AI Article Synopsis

  • Atopic dermatitis and psoriasis are both inflammatory conditions that can recur over time.
  • Some patients with atopic dermatitis treated with dupilumab may experience a shift in their symptoms, evolving from eczema-like lesions to those resembling psoriasis.
  • This report details a specific case of pustular psoriasis triggered by dupilumab, emphasizing the difficulties in diagnosing immune drift caused by biological treatments and noting that the onset of immune drift can occur more quickly than previously observed.

Article Abstract

Atopic dermatitis (AD) and psoriasis (Pso) are both recurrent inflammatory diseases. Recently, it has been reported that a small number of AD patients experience immune drift after receiving dupilumab treatment, leading to a transition from eczema-like lesions to psoriasis-like lesions. Here, we report a case of pustular psoriasis caused by dupilumab treatment for atopic dermatitis. This case underscores the diagnostic challenges associated with immune drift related to biological agents while also highlighting the shortened time frame for immune drift onset compared to previous reports.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11414640PMC
http://dx.doi.org/10.2147/JIR.S476297DOI Listing

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