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The use of Tc-tetrofosmin in the characterisation of indeterminate renal masses: a pilot study.
BJU Int
December 2024
Department of Radiology, University of North Carolina, Chapel Hill, NC, USA.
Brain SPECT and perfusion MRI: do they provide complementary information about the tumour lesion and its grading?
Clin Radiol
August 2019
Department of Nuclear Medicine, School of Medicine, University of Crete, Heraklion, Crete, Greece.
Aim: To evaluate the relative and combined utility of Tc-tetrofosmin (Tc-TF) brain single-photon-emission computed tomography (SPECT) and dynamic susceptibility contrast (DSC) perfusion magnetic resonance imaging (MRI) in grading brain gliomas.
Materials And Methods: Thirty-six patients with clinically suspected brain tumours were assessed by Tc-TF SPECT and DSC-MRI. Brain tumour malignancy was confirmed in all patients at histopathology.
Cardio-pulmonary involvement in pulmonary arterial hypertension: A perfusion and innervation scintigraphic evaluation.
J Nucl Cardiol
April 2021
Fondazione Toscana G. Monasterio, Pisa, Italy.
Background: Pulmonary arterial hypertension (PAH) is characterized by the right ventricle (RV) remodeling and pulmonary endothelial dysfunction. We studied cardiac perfusion and innervation in PAH with a cadmium-zinc-telluride (CZT) scanner and lung uptake impairment of I-metaiodobenzylguanidine (I-MIBG).
Methods: In 13 patients with newly diagnosed PAH and 11 dilated cardiomyopathies (DCM, for comparative purposes), we assessed early and delayed I-MIBG uptake ratios of lung-to-mediastinum (L/M) and heart-to-mediastinum (H/M) on anterior planar images.
Introduction: Although aneurysmal subarachnoid hemorrhage (SAH) is often complicated by myocardial injury, whether this neurogenic cardiomyopathy is associated with the modification of cardiac metabolism is unknown. This study sought to explore, by positron emission tomography/computed tomography, the presence of altered cardiac glucose metabolism after SAH.
Methods: During a 16-month period, 30 SAH acute phase patients underwent myocardial (18)F- fluorodesoxyglucose positron emission tomography ((18)F-FDGPET), (99m)Tc-tetrofosmin and (123)I-meta-iodobenzylguanidine ((123)I-mIBG) scintigraphy, respectively, assessing glucose metabolism, cardiac perfusion, and sympathetic innervation.
Association between left ventricular regional sympathetic denervation and mechanical dyssynchrony in phase analysis: a cardiac CZT study.
Eur J Nucl Med Mol Imaging
May 2014
Fondazione Toscana Gabriele Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy,
Purpose: To evaluate the relationships among myocardial sympathetic innervation, perfusion and mechanical synchronicity assessed with cardiac cadmium-zinc-telluride (CZT) scintigraphy.
Methods: A group of 29 patients underwent an evaluation of myocardial perfusion with (99m)Tc-tetrofosmin CZT scintigraphy and adrenergic innervation with (123)I-metaiodobenzylguanidine (MIBG) CZT scintigraphy. The summed rest score (SRS), motion score (SMS) and thickening score (STS), as well as the summed (123)I-MIBG defect score (SS-MIBG), were determined.
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