Gibberellic acid (GA), an ent-kaurene tetracyclic diterpene, has been considered to be a chiral pool for the chemical transformation of significant heterocyclic compounds. This chiral pool continues to influence modern synthetic chemistry as an inexpensive and versatile starting material since it is widely applied in agriculture. This review focuses on the stereoselective syntheses of bioactive agents with pharmaceutical potency prepared from Gibberellic acid.
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http://dx.doi.org/10.1002/cbdv.202401823 | DOI Listing |
Proteins
January 2025
Institute of Transformative bio-Molecules, Nagoya University, Nagoya, Japan.
In plants, sugar will eventually be exported transporters (SWEETs) facilitate the translocation of mono- and disaccharides across membranes and play a critical role in modulating responses to gibberellin (GA3), a key growth hormone. However, the dynamic mechanisms underlying sucrose and GA3 binding and transport remain elusive. Here, we employed microsecond-scale molecular dynamics (MD) simulations to investigate the influence of sucrose and GA3 binding on SWEET13 transporter motions.
View Article and Find Full Text PDFNew Phytol
January 2025
Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Singapore.
Mediator, a transcriptional coactivator, regulates plant growth and development by interacting with various transcriptional regulators. MEDIATOR15 (MED15) is a subunit in the Mediator complex potentially involved in developmental control. To uncover molecular functions of Arabidopsis MED15 in development, we searched for its interactors.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Biotechnology and Plant Improvement Laboratory, Centre of Biotechnology of Sfax, University of Sfax, P.O. Box 1177, Sfax 3018, Tunisia.
Plants are frequently challenged by a variety of microorganisms. To protect themselves against harmful invaders, they have evolved highly effective defense mechanisms, including the synthesis of numerous types of antimicrobial peptides (AMPs). Snakins are such compounds, encoded by the (Gibberellic Acid-Stimulated Arabidopsis) gene family, and are involved in the response to biotic and abiotic stress.
View Article and Find Full Text PDFPlants (Basel)
December 2024
Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education & Heilongjiang Provincial Key Laboratory of Ecological Restoration and Resource Utilization for Cold Region & Key Laboratory of Molecular Biology, College of Heilongjiang Province & School of Life Sciences, Heilongjiang University, Harbin 150080, China.
In this study, the effect of spp. on the seed germination of cabbage, a cruciferous crop, was investigated. The effects of this strain on the seed germination vigor, bud growth and physiological characteristics of Chinese cabbage were analyzed by a seed coating method.
View Article and Find Full Text PDFPlant Physiol Biochem
January 2025
School of Engineering, Anhui Agricultural University, Hefei, 230036, China. Electronic address:
In this research, we sought to investigate how high temperature, salinity, and CO affect endogenous phytohormones, photosynthesis, and redox homeostasis in Caragana korshinskii Kom (C. korshinskii) leaves, as well as to comprehensively evaluate the plant's physiological response to multiple environmental stressors. The elevated temperature (e[T]), elevated Na (e[Na]), and elevated temperature and Na (e[T-Na]) treatments increased abscisic acid (ABA) and reduced zeatin-riboside (ZR), indole-3-acetic acid (IAA), and gibberellic acid (GA).
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