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| http://dx.doi.org/10.1053/j.jvca.2024.08.037 | DOI Listing |
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- The study examines 18 and 23 specimens of two little-known anchovy species, Stolephorus grandis and Stolephorus waitei, focusing on their morphology and distribution in the Sahul Shelf coastal region.
- Researchers analyzed the mitochondrial cytochrome c oxidase subunit I (COI) gene, revealing a significant genetic divergence between the two species, with a mean genetic distance over 10%.
- The findings indicate that Stolephorus waitei, S. grandis, and another species, Stolephorus nelsoni, form a monophyletic group unique to the Sahul Shelf, with additional discussion on the evolutionary significance of specific dorsal markings in these anchovies.
Associations of demyelination in the right middle temporal gyrus and right praecuneus with visuospatial cognitive dysfunction in Alzheimer's disease.
Psychogeriatrics
January 2025
Department of Psychiatry, Nara Medical University, Nara, Japan.
Article Synopsis
- Alzheimer's disease (AD) not only affects memory but also impairments in visuospatial cognitive functions, with early-stage patients often receiving insufficient attention.
- A study involving 57 AD patients and 22 cognitively normal (CN) individuals investigated the relationship between myelin integrity (measured using T1w/T2w ratios) and visuospatial abilities through the Rey-Osterrieth Complex Figure Copy Test.
- Results revealed that lower myelin integrity in specific brain areas (right middle temporal gyrus and right praecuneus) was significantly linked to visuospatial cognitive deficits in AD patients, highlighting the importance of myelin health in cognitive function.
Background: Iridodialysis, the separation of the iris root from the ciliary body, typically results from trauma and can lead to significant visual impairment. This case report is novel as it demonstrates the successful management of iridodialysis using an extended depth of focus intraocular lens in a patient with a slightly irregular pupil.
Case Presentation: A 34-year-old Hispanic man presented with reduced vision and pain in his right eye following blunt trauma from a nail at work.
Case Report: Does the misplaced titanium mesh cage after total spondylectomy causing cervicothoracic cord compression need to be removed during revision surgery?
Front Surg
October 2024
Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Mechanical failure following total spondylectomy is a surgical challenge. The cervicothoracic junction region is a special anatomical site with complex biomechanics, and few studies have reported a detailed surgical management strategy for cases where the mesh cage subsides and compresses the spinal cord in the cervicothoracic junction region after total spondylectomy.
Case Presentation: A 56-year-old male patient experienced screw and rod fracture and mesh cage retropulsion into the spinal canal 5 years after total spondylectomy for osteochondroma in the first to third thoracic vertebrae.
TCRcost: a deep learning model utilizing TCR 3D structure for enhanced of TCR-peptide binding.
Front Genet
October 2024
School of Computer Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Introduction: Predicting TCR-peptide binding is a complex and significant computational problem in systems immunology. During the past decade, a series of computational methods have been developed for better predicting TCR-peptide binding from amino acid sequences. However, the performance of sequence-based methods appears to have hit a bottleneck.
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