AI Article Synopsis
- Obesity hypoventilation syndrome (OHS) is a condition involving obesity, daytime carbon dioxide buildup, and sleep breathing issues, and its effects on acute myocardial infarction (AMI) outcomes are not well understood.
- A study analyzed data from the National Inpatient Sample from 2016 to 2020 to assess outcomes for patients with OHS during heart attacks, specifically ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI).
- Results showed that OHS in NSTEMI patients significantly increased the risk of in-hospital death, cardiac arrest, kidney injury, need for dialysis, and respiratory failure, while STEMI patients with OHS faced higher risks for cardiac arrest
Article Abstract
Background: Obesity hypoventilation syndrome (OHS) is a condition characterized by obesity, daytime hypercapnia, and sleep-disordered breathing. The impact of OHS on outcomes in patients with acute myocardial infarction (AMI) remains poorly understood.
Methods: We conducted a retrospective analysis using data from the National Inpatient Sample (2016-2020) to evaluate the outcomes of patients with OHS admitted for ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI).
Results: Among STEMI and NSTEMI patients, 0.15 % and 0.37 % had OHS, respectively. After adjusting for confounders, OHS was associated with higher odds of in-hospital mortality, cardiac arrest, acute kidney injury, renal replacement therapy, and respiratory failure requiring intubation in NSTEMI patients. In STEMI patients, OHS was associated with higher odds of cardiac arrest, acute kidney injury, and respiratory failure.
Conclusion: OHS is associated with worse clinical outcomes in patients admitted with AMI, particularly in those with NSTEMI.
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| http://dx.doi.org/10.1016/j.rmed.2024.107813 | DOI Listing |
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