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Background: Predictive equations often inaccurately estimate energy needs in critically ill patients. This study evaluated the level of agreement between resting energy expenditure using 12 and 25 kcal/kg as recommended by the 2021 American Society for Parenteral and Enteral Nutrition critical care guidelines for nutrition support and energy expenditure measured by indirect calorimetry in patients in the intensive care unit.

Methods: An agreement study was conducted on mechanically ventilated adults who had a documented measured energy expenditure within 10 days of intensive care unit admission.

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Fruit, vegetables and discretionary food intake in Australian adults: Past trends and predicted progress towards population preventive health targets for 2030.

Aust N Z J Public Health

February 2025

Commonwealth Scientific and Industrial Research Organisation (CSIRO) Health & Biosecurity, Adelaide, South Australia 5000, Australia. Electronic address:

Objective: In Australia, 'improving access to and the consumption of a healthy diet' is a focus in the National Preventive Health Strategy. The objective of this paper is to describe the past trends and future projections of population intakes against the Strategy's targets of increasing fruit consumption to 2 servings per day; increasing vegetables to 5 servings; and reducing discretionary foods to <20% of total energy by 2030.

Methods: Self-reported intake data were available from an online survey of 275,170 Australian adults collected between 2015 and 2023.

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Astrovirus MLB1 (HAstV-MLB1) is non-enveloped RNA virus that cause acute gastroenteritis infection. Despite research progress about infection and pathogenesis of HAstV-MLB1, Currently, no vaccine has been developed to effectively combat this pathogen. The current study is based on immunoinformatics and reverse vaccinology approaches to design next-generation, multi-epitope-based vaccine models against HAstV-MLB1.

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Cloning, Expression, Characterization and in silico studies of L-asparaginase from Vibrio sp. (GBPx3).

Biochimie

March 2025

Department of Medical Biotechnology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran; Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran. Electronic address:

L-asparaginase is a critical therapeutic enzyme for treating acute lymphoblastic leukemia (ALL), a common childhood malignancy. In this study, the L-asparaginase coding sequence from halophilic Vibrio sp. (GBPx3) was cloned, expressed in Escherichia coli, and characterized.

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Investigation and analysis of the proton-induced reactions on Cu, Cu, and Cu to produce Zn radioisotopes for medical applications.

Appl Radiat Isot

March 2025

Ministry of Education, Directorate of Education, Al-Rasafa Al-Uola, Baghdad, Iraq.

The phenomenological and microscopic level density models were utilized within the TALYS 2.0 software to simulate the cross-sections of proton-induced reactions on both natural and enriched copper. This process resulted in the production of the zinc radioisotopes Zn, Zn, and Zn, which hold significance in diagnostic and therapeutic medicine.

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