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SIOOT recommendations for the optimal application of the oxygen-ozone therapy in clinical medicine.
Int Immunopharmacol
January 2025
Italian Scientific Society of Oxygen-Ozone Therapy (SIOOT), Bergamo, Italy; High School Master of Oxygen-Ozone Therapy, University of Pavia, Pavia, Italy.
Oxygen-ozone therapy has garnered increasing attention for its potential therapeutic applications, yet its widespread adoption is hindered by inconsistent protocols and a lack of standardized guidelines. Standardizing these protocols is essential to ensure the safety, efficacy, and reproducibility of treatments. Advanced training for physicians and caregivers is paramount, equipping them with evidence-based knowledge and practical expertise to administer this therapy effectively while avoiding unverified or misleading innovative approaches.
View Article and Find Full Text PDFOzone therapy for knee osteoarthritis: a literature visualization analysis of research hotspots and prospects.
Med Gas Res
December 2024
Department of Knee Preservation Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
Medical ozone is a molecule composed of three oxygen atoms with anti-inflammatory, analgesic, and antioxidant functions. Ozone therapy (O3 or O2- O3) for knee osteoarthritis has gradually received increasing attention from researchers in recent years. Here, we discuss the research hotspots and development trends of ozone therapy for knee osteoarthritis through literature visualization and analysis.
View Article and Find Full Text PDFCombined Oxygen-Ozone and Porcine Injectable Collagen Therapies Boosting Efficacy in Low Back Pain and Disability.
Diagnostics (Basel)
October 2024
Division of Rehabilitation, ASST Fatebenefratelli-Sacco Hospital, Fatebenefratelli Institution, 3, Piazza Principessa Clotilde, 20121 Milan, Italy.
Intervertebral disc degeneration is the most common cause of low back pain (LBP), and lumbosciatica is a major challenge to healthcare systems worldwide. For years, ozone therapy has been used with excellent results in intervertebral disc disease and in patients with LBP. In vitro studies have demonstrated the positive action of porcine collagen in extracellular matrix remodeling and homeostasis.
View Article and Find Full Text PDFEfficacy of oxygen-ozone therapy against the pro-necrotic action of Loxosceles rufescens toxic bite.
Int Immunopharmacol
December 2024
Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Italy, strada Le Grazie 9, 37134 Verona, Italy. Electronic address:
The efficacy of ultrasonography-guided oxygen-ozone therapy versus corticosteroids in patients with knee osteoarthritis: A multicenter randomized controlled trial.
J Back Musculoskelet Rehabil
November 2024
Ankara Gaziler Phsycial Therapy and Rehabilitation Education and Research Hospital, University of Health Sciences, Ankara, Turkey.
Background: Osteoarthritis (OA) is a widely-known disease distinguished by the breakdown of joint cartilage, leading to pain and morning stiffness. In this context, the role of corticosteroids is well known, but there is still a gap of knowledge on the duty of oxygen-ozone therapy (O2-O3).
Objective: To evaluate for effectiveness of ultrasound-guided O2-O3 injections compared with corticosteroid injections among patients diagnosed with knee OA.
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