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Response to Goddu et al.: new ways of characterizing and acquiring knowledge.
Trends Cogn Sci
November 2024
Wu-Tsai Institute, Yale University, New Haven, CT, USA; Department of Philosophy, Yale University, New Haven, CT, USA; Munich Center for Mathematical Philosophy, Ludwig Maximilian University, Munich, Germany. Electronic address:
Preschoolers' Comprehension of Functional Metaphors.
Open Mind (Camb)
July 2024
Department of Psychology, University of California - Berkeley, Berkeley, CA.
Previous work suggests that preschoolers often misunderstand metaphors. However, some recent studies demonstrate that preschoolers can represent abstract relations, suggesting that the cognitive foundations of metaphor comprehension may develop earlier than previously believed. The present experiments used novel paradigms to explore whether preschoolers ( = 200; 4-5 years; 100 males, 100 females; predominantly White) can understand metaphors based on abstract, functional similarities.
View Article and Find Full Text PDFSpatially fractionated stereotactic body radiation therapy (Lattice) for large tumors.
Adv Radiat Oncol
January 2021
Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri.
Purpose: Stereotactic body radiation therapy (SBRT) has demonstrated clinical benefits for patients with metastatic and/or unresectable cancer. Technical considerations of treatment delivery and nearby organs at risk can limit the use of SBRT in large tumors or those in unfavorable locations. Spatially fractionated radiation therapy (SFRT) may address this limitation because this technique can deliver high-dose radiation to discrete subvolume vertices inside a tumor target while restricting the remainder of the target to a safer lower dose.
View Article and Find Full Text PDFChronic exposure of the RAW246.7 macrophage cell line to HO leads to increased catalase expression.
Free Radic Biol Med
October 2018
Department of Biology, Sonoma State University, 1801 E. Cotati Ave, Rohnert Park, CA 94928, United States. Electronic address:
Altered cellular redox states have been associated with a variety of chronic diseases, especially those correlated with inflammation. One of the primary oxidants generated during the inflammatory response is hydrogen peroxide (HO). Macrophages in particular are thought to produce large amounts of HO, however they must somehow protect themselves from the potentially lethal concentrations they produce.
View Article and Find Full Text PDFNormalize the response of EPID in pursuit of linear accelerator dosimetry standardization.
J Appl Clin Med Phys
January 2018
Department of Radiation Oncology, Washington University, St. Louis, MO, USA.
Normalize the response of electronic portal imaging device (EPID) is the first step toward an EPID-based standardization of Linear Accelerator (linac) dosimetry quality assurance. In this study, we described an approach to generate two-dimensional (2D) pixel sensitivity maps (PSM) for EPIDs response normalization utilizing an alternative beam and dark-field (ABDF) image acquisition technique and large overlapping field irradiations. The automated image acquisition was performed by XML-controlled machine operation and the PSM was generated based on a recursive calculation algorithm for Varian linacs equipped with aS1000 and aS1200 imager panels.
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