Transcription regulation through selective partitioning: Weak interactions with a strong foundation.

Mol Cell

Department of Biochemistry, University of Colorado, Boulder, CO 80303, USA. Electronic address:

Published: September 2024

In this issue of Molecular Cell, De La Cruz, Pradhan, Veettil et al. examine how selective partitioning of proteins via low-affinity IDR-dependent interactions may help regulate RNA polymerase II (RNA Pol II) function and identify sequence features that drive partitioning in cells.

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http://dx.doi.org/10.1016/j.molcel.2024.08.029DOI Listing

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